p-alpha-DO Probe Detail MGI Mouse MGI:13432

p-alpha-DO Probe Detail

Name

p-alpha-DO
Sequence Type

cDNA
ID

MGI:13432
Region Covered

encodes gene segments Tcra-V13.1, Tcra-J, Tcra-C and 3' untranslated sequence
Vector Type

Plasmid
Insert Site

Hind/EcoRI
Insert Size

1.2 kb

Species

mouse, laboratory
Tissue

T-lymphocyte
Cell Line

hybridoma cell line DP.11.10

Tcra-J	T cell receptor alpha, joining region
Trav5-4	T cell receptor alpha variable 5-4
Trac	T cell receptor alpha constant

J:8208 Epstein R, et al., J Exp Med. 1986 Apr 1;163(4):759-73

Notes: A 475 bp HindIII/RsaI fragment specific for Tcra-V13 was isolated from p[a]DO and used in Southern analysis.

Endonuclease	Gene	Allele	Fragments	Strains
BglI	Trav5-4	c	not given	SJL/J
BglI	Trav5-4	j	not given	BALB/cKe, SJL/J
EcoRI	Trav5-4	c	3.3,1.0kb	SJL/J
EcoRI	Trav5-4	j	0.7kb	BALB/cKe, SJL/J
KpnI	Trav5-4	c	not given	SJL/J
KpnI	Trav5-4	j	not given	BALB/cKe, SJL/J

J:7926 Yague J, et al., The T cell receptor: the alpha and beta chains define idiotype, and antigen and MHC specificity. Cell. 1985 Aug;42(1):81-7

J:8208 Epstein R, et al., The cytotoxic T cell response to the male-specific histocompatibility antigen (H-Y) is controlled by two dominant immune response genes, one in the MHC, the other in the Tar alpha-locus. J Exp Med. 1986 Apr 1;163(4):759-73

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/17/2024 MGI 6.24