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FceRI-alpha-cDNA Probe Detail
Nucleotide
Probe/Clone
  • Name
    FceRI-alpha-cDNA
  • Sequence Type
    cDNA
  • ID
    MGI:13474
  • Region Covered
    composite cDNA is ~1 kb in length
  • Vector Type
    Plasmid
  • Insert Site
    StyI
  • Insert Size
    600bp
  • Synonyms
    Fcer1a cDNA, FceRIalpha
Source
  • Species
    rat
  • Tissue
    leukemia
  • Tissue Description
    basophilic leukemia
Genes
Fcer1a Fc receptor, IgE, high affinity I, alpha polypeptide
Polymorphisms
J:9397 Huppi K, et al., J Immunol. 1988 Oct 15;141(8):2807-10
Notes: A 600 bp StyI fragment from FceRI[a] cDNA was utilized for Southern analysis. RFLV band sizes are estimates from gel photos.
Endonuclease Gene Allele Fragments Strains
BamHI Fcer1a a 9.5,6.6,3.0,1.3,0.9kb AKR/N, BALB/cAn, BALB/cHeA, BALB/cJ, NZB/BlNJ, SJL/JLw
b 8.0,6.6,3.0,1.3kb C57BL/6J, C57BL/10N, C57L/J, DBA/2N, O20/A
c 8.0,3.8,3.0,1.3,0.9kb C58/J, STS/A, SWR/J
J:10118 Huppi K, et al., J Immunol. 1989 Dec 1;143(11):3787-91
Endonuclease Gene Allele Fragments Strains
BamHI Fcer1a a not given AKR/N, BALB/c, NZB/BlNJ, SJL/JLw
b not given C57BL/6J, C57BL/10N, C57L/J, DBA/2N, O20/A
c not given C58/J, STS/A, SWR/J
J:10129 Kingsmore SF, et al., EMBO J. 1989 Dec 20;8(13):4073-80
Notes: Only the distinguishing fragment in M.spretus listed.
Endonuclease Gene Allele Fragments Strains
TaqI Fcer1a c absent C3H/HeJ-Faslgld/J
s ~7.5kb M. spretus
J:10139 Moseley WS, et al., Genomics. 1989 Nov;5(4):899-905
Endonuclease Gene Allele Fragments Strains
TaqI Fcer1a c absent C3H/HeJ-Faslgld/J
s ~8.0kb M. spretus
References
J:8867 Kinet JP, et al., A cDNA presumptively coding for the alpha subunit of the receptor with high affinity for immunoglobulin E [published erratum appears in Biochemistry 1988 Nov 15;27(23):8694]. Biochemistry. 1987 Jul 28;26(15):4605-10
J:9397 Huppi K, et al., Receptors for Fc epsilon and Fc gamma are linked on mouse chromosome 1. J Immunol. 1988 Oct 15;141(8):2807-10
J:10118 Huppi K, et al., Gene mapping of the three subunits of the high affinity FcR for IgE to mouse chromosomes 1 and 19. J Immunol. 1989 Dec 1;143(11):3787-91
J:10129 Kingsmore SF, et al., A 6000 kb segment of chromosome 1 is conserved in human and mouse. EMBO J. 1989 Dec 20;8(13):4073-80
J:10139 Moseley WS, et al., Definition of mouse chromosome 1 and 3 gene linkage groups that are conserved on human chromosome 1: evidence that a conserved linkage group spans the centromere of human chromosome 1. Genomics. 1989 Nov;5(4):899-905
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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11/12/2024
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