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PC6684 Probe Detail
Nucleotide
Probe/Clone
  • Name
    PC6684
  • Sequence Type
    genomic
  • ID
    MGI:13587
  • Region Covered
    encodes the Igk-V11, Igk-J(1-4) and Igk-C gene segments
  • Vector Type
    Phage
  • Insert Site
    HindIII
  • Insert Size
    4 kb
  • Note
    Pc6884 encodes a nonproductive allele of Igk-J and Igk-V11.
  • Synonyms
    p6684, p6684k-
Source
  • Species
    mouse, laboratory
  • Strain
    NZB
  • Tissue
    plasmacytoma
Genes
Igkc immunoglobulin kappa constant
Igk-J immunoglobulin kappa chain, joining region
Igk-V11 immunoglobulin kappa chain variable 11 (V11)
Polymorphisms
J:9339 D'Hoostelaere L, et al., Curr Top Microbiol Immunol. 1988;137:116-29
Endonuclease Gene Allele Fragments Strains
BamHI Igk-V11 a multiple AKR, BALB/c, C57BL/6, PL, SJL
b multiple ABP, C58, NZB
c multiple CE, O20
References
J:7956 Kelley DE, et al., Nonproductive kappa immunoglobulin genes: recombinational abnormalities and other lesions affecting transcription, RNA processing, turnover, and translation. Mol Cell Biol. 1985 Jul;5(7):1660-75
J:9339 D'Hoostelaere L, et al., The organization of the immunoglobulin kappa locus in mice. Curr Top Microbiol Immunol. 1988;137:116-29
J:10769 D'Hoostelaere LA, et al., Characterization of new mouse V kappa groups. J Immunol. 1990 Oct 15;145(8):2706-12
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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11/19/2024
MGI 6.24 		The Jackson Laboratory