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clone 603-18 Probe Detail
Nucleotide
Probe/Clone
  • Name
    clone 603-18
  • Sequence Type
    genomic
  • ID
    MGI:14567
  • Region Covered
    encodes Tnfb exon 4, intergenic sequence, all 4 Tnfa exons and 3'-flanking sequence
  • Vector Type
    Phage
  • Insert Size
    ~16 kb
Source
  • Species
    mouse, laboratory
  • Strain
    C57BL/6
  • Tissue
    T-lymphocyte
Genes
Lta lymphotoxin A
Tnf tumor necrosis factor
Sequences
Polymorphisms
J:8762 Gardner SM, et al., J Immunol. 1987 Jul 15;139(2):476-83
Notes: An 800 bp SmaI/EcoRI fragment encoding Tnfa intron 3 and exon 4 was isolated from clone 603-18 and used in Southern analysis.
Endonuclease Gene Allele Fragments Strains
PstI Tnf a 9.5kb 129P3/J, A/J, BALB/cAnPt, C57BL/6, C57BL/10, DBA/2J, LP/J, O20/A, PL/J, STS/A, YBR
b 8.5kb AKR/N, C3H/HeN, C57BR, CBA/CaH, CE/J, DBA/1J, RIIIS/J, SM/J
XbaI Tnf a 6.7kb A/J, BALB/c, BALB/cAnPt, DBA/2J, PL/J, SM/J, YBR
b 6.5kb 129P3/J, AKR/N, C3H/HeN, C57BL/6, C57BL/10, C57BR, CBA/CaH, CE/J, DBA/1J, LP/J, O20/A, RIIIS/J, STS/A
XbaI/B Tnf a 4.3kb A/J, BALB/cAnPt, BALB/cHeA
b 6.5kb AKR/N, C57BL/10, STS/A
c 6.3kb O20/A
References
J:8762 Gardner SM, et al., Mouse lymphotoxin and tumor necrosis factor: structural analysis of the cloned genes, physical linkage, and chromosomal position. J Immunol. 1987 Jul 15;139(2):476-83

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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory