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pUCV-beta-4 Probe Detail
Nucleotide
Probe/Clone
  • Name
    pUCV-beta-4
  • Sequence Type
    cDNA
  • ID
    MGI:14862
  • Region Covered
    encodes Tcrb-V4, Tcrb-D (Db2.1) and Tcrb-J (Jb2.6) gene segments
  • Vector Type
    Phage
  • Synonyms
    TB3
Source
  • Species
    mouse, laboratory
  • Strain
    C57BL/Ka
  • Tissue
    thymocyte
Genes
Tcrb-D T cell receptor beta, D region
Tcrb-J T cell receptor beta, joining region
Trbv2 T cell receptor beta, variable 2
Polymorphisms
J:9665 Klotz JL, et al., Immunogenetics. 1989;29(3):191-201
Notes: Haplotype RFLP entry is a composite of data from this reference. Allele assignments for haplotypes are shown to be consistent with those in Mouse Genome 1990; 86:188. Additional unique types are listed for M.caroli, M.hortulanus, M.musclus-Denmark, M.musculus-Yugoslavia, M.musculus-Brno. Tcrb alleles are haplotypes determined by a combination of V and J region typings.
Endonuclease Gene Allele Fragments Strains
Not Specified Trbv2 a n/a C57L/J, SJL/J, SWR/J
b n/a M. m. domesticus
c n/a AKR/J, BALB/cJ, C3H/HeJ, C57BL/6J, C57BL/10J, C58/J, CBA/J
d n/a A/J, MRL, NZB, ST/bJ
e n/a NZW
f n/a C57BR/cdJ
g n/a BXSB/MpJ
h n/a M. m. castaneus
s n/a M. spretus
TaqI Trbv2 a not given AKR/J, BALB/cJ, BXSB/MpJ, C3H/HeJ, C57BL/6J, C57BL/10J, C57BR/cdJ, C57L/J, C58/J, CBA/J, SJL/J, SWR/J
b not given A/J, MRL, NZB, NZW, ST/bJ
References
J:7995 Barth RK, et al., The murine T-cell receptor uses a limited repertoire of expressed V beta gene segments. Nature. 1985 Aug 8-14;316(6028):517-23
J:9665 Klotz JL, et al., Restriction fragment length polymorphisms of the mouse T-cell receptor gene families [published erratum appears in Immunogenetics 1989;30(3):235]. Immunogenetics. 1989;29(3):191-201
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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11/12/2024
MGI 6.24 		The Jackson Laboratory