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86T1 Probe Detail
Nucleotide
Probe/Clone
  • Name
    86T1
  • Sequence Type
    cDNA
  • ID
    MGI:15056
  • Region Covered
    includes a portion of the Tcrb-V1 gene segment as well as the Tcrb-D Tcrb-J Tcrb-C ([b]2) gene segments
  • Child Clone
    Tcrb cDNA1
  • Vector Type
    Phage
  • Insert Site
    EcoRI
  • Insert Size
    938 bp
  • Note
    Probe insert was subcloned into pUC9. Hybridizes to both Tcrb-C gene segments [b]1 and [b]2.
Source
  • Species
    mouse, laboratory
  • Strain
    BALB/c
  • Tissue
    thymocyte
Genes
Tcrb-C T cell receptor beta, constant region
Tcrb-D T cell receptor beta, D region
Tcrb-J T cell receptor beta, joining region
Trbv5 T cell receptor beta, variable 5
Sequences
X00438 (GenBank | EMBL | ENA | DDBJ | MGI Sequence Detail)
Polymorphisms
J:8024 D'Hoostelaere LA, et al., Immunogenetics. 1985;22(3):277-83
Endonuclease Gene Allele Fragments Strains
BamHI Tcrb a 6.4kb SJL/JLw
b 12kb CB6.C3-Hoxa13Hd
J:9125 Seldin MF, et al., Immunogenetics. 1988;27(5):396-8
Endonuclease Gene Allele Fragments Strains
BamHI Trbv5 b 7.0,12.0kb C3H/HeJ-Faslgld/J
s 7.0,7.5kb M. spretus
J:9361 Rueff-Juy D, et al., Immunogenetics. 1988;28(4):233-9
Notes: Only the diagnostic bands are listed.
Endonuclease Gene Allele Fragments Strains
EcoRI Tcrb-C m 8.4,2.3kb MAI
s 11.0,3.0kb SJL
References
J:7354 Hedrick SM, et al., Sequence relationships between putative T-cell receptor polypeptides and immunoglobulins. Nature. 1984 Mar 8-14;308(5955):153-8
J:7995 Barth RK, et al., The murine T-cell receptor uses a limited repertoire of expressed V beta gene segments. Nature. 1985 Aug 8-14;316(6028):517-23
J:8024 D'Hoostelaere LA, et al., Localization of CT beta and C kappa on mouse chromosome 6. Immunogenetics. 1985;22(3):277-83
J:9125 Seldin MF, et al., Mapping of the Ly-4 (L3T4) T-cell differentiation antigen on mouse chromosome 6 by the use of RFLPs in an interspecific cross. Immunogenetics. 1988;27(5):396-8
J:9361 Rueff-Juy D, et al., Mapping of Igk-V genes using backcrossed laboratory and wild mice. Immunogenetics. 1988;28(4):233-9
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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06/12/2024
MGI 6.13 		The Jackson Laboratory