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8/10-2-gamma-1.1 Probe Detail
Nucleotide
Probe/Clone
  • Name
    8/10-2-gamma-1.1
  • Sequence Type
    cDNA
  • ID
    MGI:15057
  • Region Covered
    encodes 5' untranslated sequence, Tcrg-V2, -J2, -C2 gene segments and 3' untranslated sequence
  • Child Clones
    probe a, probe b
  • Vector Type
    Phage
  • Insert Site
    EcoRI
  • Note
    The nomenclature used here to describe the Tcrg complex is suggested by S. Tonegawa. For more information see Takagaki (1989) J Immunol 142:2112-2121. Probe detects C[g]1, C[g]2, and C[g]3 genes
Source
  • Species
    mouse, laboratory
  • Strain
    C57BL/10
  • Cell Line
    CTL line 8/10-2
Genes
Tcrg-C T cell receptor gamma, constant region
Tcrg-J T cell receptor gamma, joining region
Trgv1 T cell receptor gamma, variable 1
Trgv2 T cell receptor gamma variable 2
Trgv3 T cell receptor gamma, variable 3
Polymorphisms
J:10143 Nobuhara H, et al., Immunogenetics. 1989;30(6):405-13
Notes: A 530 bp HinfI fragment derived from 8/10-2[g]1.1 was used in Southern analysis.
Endonuclease Gene Allele Fragments Strains
BamHI Tcrg-C a 11,8,7,4kb A/J, BALB/cAnN, C57BL/6J, NZB/BlNJ, SJL/J, SK/Cam
b not given AKR/J, AU/SsJ, C57L/J, I/LnJ, LP.RIII-H2r H2-T18b/SnJ, M. m. molossinus, P/J, SL/Qdj
c not given C3H/HeJ, C57BL/10J, C58/J, CBA/J, DBA/1J, DBA/2J, M. m. castaneus, MA/MyJ, PL/J, RBF/DnJ, RIIIS/J, SM/J
EcoRI Tcrg-C a 13.4,10.5,7.5kb A/J, BALB/cAnN, C57BL/6J, NZB/BlNJ, SJL/J, SK/Cam
b 15,10.5,6.9kb AKR/J, AU/SsJ, C57L/J, I/LnJ, LP.RIII-H2r H2-T18b/SnJ, M. m. molossinus, P/J, SL/Qdj
c 15,10.5kb C3H/HeJ, C57BL/10J, C58/J, CBA/J, DBA/1J, DBA/2J, M. m. castaneus, MA/MyJ, PL/J, RBF/DnJ, RIIIS/J, SM/J
HindIII Tcrg-C a 3,2.7,1.2,0.8kb A/J, BALB/cAnN, C57BL/6J, NZB/BlNJ, SJL/J, SK/Cam
b not given AKR/J, AU/SsJ, C57L/J, I/LnJ, LP.RIII-H2r H2-T18b/SnJ, M. m. molossinus, P/J, SL/Qdj
c not given C3H/HeJ, C57BL/10J, C58/J, CBA/J, DBA/1J, DBA/2J, M. m. castaneus, MA/MyJ, PL/J, RBF/DnJ, RIIIS/J, SM/J
References
J:8270 Iwamoto A, et al., T cell-specific gamma genes in C57BL/10 mice. Sequence and expression of new constant and variable region genes. J Exp Med. 1986 May 1;163(5):1203-12
J:10143 Nobuhara H, et al., Polymorphism of T-cell receptor genes among laboratory and wild mice: diverse origins of laboratory mice. Immunogenetics. 1989;30(6):405-13
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11/12/2024
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