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pK3A Probe Detail
Nucleotide
Probe/Clone
  • Name
    pK3A
  • Sequence Type
    cDNA
  • ID
    MGI:15247
  • Region Covered
    encodes amino acids 165-791
  • Child Clones
    Kit cDNA-1, Kit cDNA-2, Kit cDNA-3
  • Vector Type
    Phage
  • Insert Site
    EcoRI
  • Insert Size
    1.85kb
  • Synonyms
    Probe A
Source
  • Species
    mouse, laboratory
  • Strain
    BALB/c
  • Tissue
    brain
Genes
Kit KIT proto-oncogene receptor tyrosine kinase
Polymorphisms
J:9374 Geissler EN, et al., Cell. 1988 Oct 7;55(1):185-92
Endonuclease Gene Allele Fragments Strains
BamHI Kit +/+ 17,9.6,7,5.5,2kb C3H
W<44> 9.6,7,5.5,2,10kb B6.C3-KitW-44J
W/+ 17,9.6,7,5.5,2,6.5kb C3H/HeJ-KitW-x
BglII Kit +/+ 9.4,6.6,5,3.3,2.5,2kb C3H
W<44> 9.4,6.6,5,3.3,2kb B6.C3-KitW-44J
W/+ 9.4,6.6,5,3.3,2.5,2kb C3H/HeJ-KitW-x
EcoRI Kit +/+ 17,8,5,3,1kb C3H
W<44> 8,5,3,1,14,7kb B6.C3-KitW-44J
W/+ 17,8,5,3,1,3.6kb C3H/HeJ-KitW-x
PstI Kit +/+ 7,5.2,3.8,3.5,2.5,1.5, 0.8kb C3H
W<44> 5.2,3.8,3.5,2.5,1.5,0.8, 6.5kb B6.C3-KitW-44J
W/+ 7,5.2,3.8,3.5,2.5,1.5,0.8,2.3kb C3H/HeJ-KitW-x
J:19185 Grosson CL, et al., Mamm Genome. 1994 Jul;5(7):424-8
Endonuclease Gene Allele Fragments Strains
PvuII Kit b 7.0,4.5,3.7,2.4,1.4,1.2,1.1kb C57BL/6
s 2.8,2.2,1.3kb M. spretus
References
J:9374 Geissler EN, et al., The dominant-white spotting (W) locus of the mouse encodes the c-kit proto-oncogene. Cell. 1988 Oct 7;55(1):185-92
J:11255 Smith EA, et al., Mouse platelet-derived growth factor receptor alpha gene is deleted in W19H and patch mutations on chromosome 5. Proc Natl Acad Sci U S A. 1991 Jun 1;88(11):4811-5
J:19185 Grosson CL, et al., Synteny conservation of the Huntington's disease gene and surrounding loci on mouse Chromosome 5. Mamm Genome. 1994 Jul;5(7):424-8
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/10/2024
MGI 6.24 		The Jackson Laboratory