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probe 1 Probe Detail
Nucleotide
Probe/Clone
  • Name
    probe 1
  • Sequence Type
    genomic
  • ID
    MGI:16824
  • Region Covered
    encodes sequence ~5 kb 3' of H-2Ob
  • Parent Clone
  • Insert Site
    SmaI/HpaI
  • Insert Size
    2.0kb
  • Synonyms
    probe 2, probe 14
Source
  • Species
    mouse, laboratory
  • Strain
    BALB/c
  • Tissue
    liver
Genes
H2-Ob histocompatibility 2, O region beta locus
Polymorphisms
J:6885 Steinmetz M, et al., Nature. 1982 Nov 4;300(5887):35-42
Endonuclease Gene Allele Fragments Strains
BamHI H2-Ob b 15kb A.SW-H2s/Sn, BALB/c
c 16kb A.TL-H2t1, C3H, C57BL/6
EcoRI H2-Ob b 18kb B10.TL-H2r1, C3H
c 9kb A.SW-H2s/Sn, BALB/c, C57BL/6
J:15532 Steinmetz M, et al., EMBO J. 1984 Dec 1;3(12):2995-3003
Endonuclease Gene Allele Fragments Strains
EcoRI H2-Ob a 7.0kb B10.KPA44, B10.STA10, BALB/c
b 8.2kb A.SW-H2s/Sn, B10.CAS2, B10.STA62, C57BL/10
c 15.3kb AKR, B10.DRB62
HindIII H2-Ob a 6.7,2.9kb A.SW-H2s/Sn, AKR, B10.DRB62, B10.KPA44, B10.STA62, BALB/c, C57BL/10
b 6.7,4.5kb B10.STA10
c 6.7,3.0 B10.CAS2
KpnI H2-Ob a 32kb B10.CAS2, B10.KPA44, BALB/c
b 23kb A.SW-H2s/Sn, AKR, B10.DRB62, B10.STA10, B10.STA62, C57BL/10
J:8224 Steinmetz M, et al., Cell. 1986 Mar 28;44(6):895-904
Endonuclease Gene Allele Fragments Strains
EcoRI H2-Ob a not given B10.A-H2a, B10.AQR-H2y1
b not given T138
EcoRV H2-Ob a not given B10.A-H2a, B10.AQR-H2y1
b not given T138
HpaI H2-Ob a not given B10.A-H2a, B10.AQR-H2y1
b not given T138
XbaI H2-Ob a not given C57BL/6, CAS3(R0), CAS3(R18)
b not given B10.CAS3, CAS3(R11)
References
J:6885 Steinmetz M, et al., A molecular map of the immune response region from the major histocompatibility complex of the mouse. Nature. 1982 Nov 4;300(5887):35-42
J:15532 Steinmetz M, et al., Tracts of high or low sequence divergence in the mouse major histocompatibility complex. EMBO J. 1984 Dec 1;3(12):2995-3003
J:8224 Steinmetz M, et al., Gene organization and recombinational hotspots in the murine major histocompatibility complex. Cell. 1986 Mar 28;44(6):895-904

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
09/03/2024
MGI 6.24
The Jackson Laboratory