probe 3 Probe Detail MGI Mouse MGI:16825

probe 3 Probe Detail

Name

probe 3
Sequence Type

genomic
ID

MGI:16825
Region Covered

encodes most of H-2Aa
Parent Clone

clone 24.2
Insert Site

EcoRI/BamHI
Insert Size

4.7 kb
Synonyms

probe 2

Species

mouse, laboratory
Strain

BALB/c
Tissue

sperm

H2-Aa

histocompatibility 2, class II antigen A, alpha

J:6885 Steinmetz M, et al., Nature. 1982 Nov 4;300(5887):35-42

Endonuclease	Gene	Allele	Fragments	Strains
HindIII	H2-Aa	a	8.0kb	A.TL-H2^t1, C3H
		b	7.5kb	A.SW-H2^s/Sn, C57BL/6
		c	11.0kb	BALB/c
KpnI	H2-Aa	a	16kb	A.SW-H2^s/Sn, B10.A-H2^h4/(4R), C3H
		b	>20kb	B10.A-H2ⁱ⁵/(R5)SgSn, C57BL/6
		c	13.0kb	B10.GD-H2^g2, BALB/c

J:15532 Steinmetz M, et al., EMBO J. 1984 Dec 1;3(12):2995-3003

Endonuclease	Gene	Allele	Fragments	Strains
BamHI	H2-Aa	a	5.6kb	A.SW-H2^s/Sn, B10.CAS2, B10.DRB62, BALB/c
		b	9.5kb	B10.KPA44
		c	6.0kb	B10.STA10, B10.STA62, C3H, C57BL/6
HindIII	H2-Aa	a	11.0kb	BALB/c
		b	8.2,1.5kb	C57BL/6
		c	8.2,2.5kb	A.SW-H2^s/Sn, B10.CAS2, B10.DRB62, B10.KPA44, B10.STA10
		d	8.5kb	C3H
		e	8.5,1.5kb	B10.STA62
KpnI	H2-Aa	a	13kb	BALB/c
		b	22kb	B10.CAS2, B10.STA62, C57BL/6
		c	17kb	A.SW-H2^s/Sn, B10.STA10, C3H
		d	20kb	B10.DRB62, B10.KPA44

J:6885 Steinmetz M, et al., A molecular map of the immune response region from the major histocompatibility complex of the mouse. Nature. 1982 Nov 4;300(5887):35-42

J:15532 Steinmetz M, et al., Tracts of high or low sequence divergence in the mouse major histocompatibility complex. EMBO J. 1984 Dec 1;3(12):2995-3003

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