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VrDNA Probe Detail
Nucleotide
Probe/Clone
  • Name
    VrDNA
  • Sequence Type
    Not Specified
  • ID
    MGI:17150
  • Region Covered
    5' to the origin of transcription, includes 13 repeating elements
  • Vector Type
    Plasmid
  • Insert Size
    ~1.7kb
  • Synonyms
    B-28
Source
  • Species
    mouse, laboratory
Genes
Rnr11 ribosomal RNA, Chr 11 cluster
Rnr12 ribosomal RNA, Chr 12 cluster
Rnr13 rRNA, Chr 13 cluster
Rnr15 ribosomal RNA, Chr 15 cluster
Rnr16 ribosomal RNA, Chr 16 cluster
Rnr18 ribosomal RNA, Chr 18 cluster
Rnr4 ribosomal RNA, Chr 4 cluster
Rnr19-1 ribosomal RNA, Chr 19-1 cluster
Polymorphisms
J:6869 Arnheim N, et al., Proc Natl Acad Sci U S A. 1982 Aug;79(15):4677-80
Endonuclease Gene Allele Fragments Strains
HindII Rnr12 a 1.6,1.33,0.77kb RB5Bnr/Ei
b 2.7,1.6,1.33,1.2,0.77kb C57BL/6J
c 2.7,1.75,1.6,1.33,0.65kb C3H/HeJ
SalI Rnr12 b 2.7,1.6,1.33,1.2,0.77kb C57BL/6J
c 2.7,1.75,1.33,0.65kb C3H/HeJ
J:9804 Nelson FK, et al., Mol Cell Biol. 1989 Mar;9(3):1284-8
Endonuclease Gene Allele Fragments Strains
HindII Rnr12 a absent 129P3/J, C3H/HeJ
d 1.2kb DBA/1J
J:3749 Johnson KR, et al., Mamm Genome. 1993;4(1):49-52
Notes: A 1.7kb SalI fragment was used as hybridization probe. Multiple Rnr-loci can be scored on a single Southern blot.
Endonuclease Gene Allele Fragments Strains
TaqI Rnr11 b absent C57BL/6J
c 1.55kb CAST/EiJ
TaqI Rnr12 b 2.35,1kb C57BL/6J, C57BL/6JEiJ
c 0.75,1.35kb CAST/EiJ
s absent M. spretus
TaqI Rnr15 b 1.2kb C57BL/6J
s absent M. spretus
TaqI Rnr16 b 0.65kb C57BL/6J, C57BL/6JEiJ
s absent M. spretus
TaqI Rnr18 b absent C57BL/6J
c 1.7,2.1kb CAST/EiJ
J:4594 Eicher EM, et al., Mamm Genome. 1993;4(4):226-9
Endonuclease Gene Allele Fragments Strains
TaqI Rnr4 b not given C57BL/6J
s 1.9,2.0kb M. spretus
TaqI Rnr13 b not given C57BL/6J
s 3.0kb M. spretus
TaqI Rnr19-1 b not given C57BL/6J
s 2.1kb M. spretus
References
J:6869 Arnheim N, et al., Distribution of ribosomal gene length variants among mouse chromosomes. Proc Natl Acad Sci U S A. 1982 Aug;79(15):4677-80
J:9804 Nelson FK, et al., Mitotic recombination is responsible for the loss of heterozygosity in cultured murine cell lines. Mol Cell Biol. 1989 Mar;9(3):1284-8
J:3749 Johnson KR, et al., Genetic mapping of variable length rDNA segments to centromeric regions of mouse chromosomes 11, 12, 15, 16, and 18. Mamm Genome. 1993;4(1):49-52
J:4594 Eicher EM, et al., Molecular markers that define the distal ends of mouse autosomes 4, 13, and 19 and the sex chromosomes. Mamm Genome. 1993;4(4):226-9
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/10/2024
MGI 6.24 		The Jackson Laboratory