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pA1.3 Probe Detail
Nucleotide
Probe/Clone
  • Name
    pA1.3
  • Sequence Type
    cDNA
  • ID
    MGI:18183
  • Region Covered
    encodes 0.12kb 5' untranslated sequence, 0.79kb coding region, 0.31kb 3' untranslated sequence
  • Vector Type
    Plasmid
  • Insert Site
    BstXI
  • Insert Size
    1.21kb
Source
  • Species
    mouse, laboratory
  • Strain
    C57BL/6
  • Tissue
    T-lymphocyte
  • Cell Line
    lymphoma cell line EL4
Genes
Klra killer cell lectin-like receptor, subfamily A
Klra8 killer cell lectin-like receptor, subfamily A, member 8
Klra5 killer cell lectin-like receptor, subfamily A, member 5
Klra4 killer cell lectin-like receptor, subfamily A, member 4
Klra7 killer cell lectin-like receptor, subfamily A, member 7
Klra6 killer cell lectin-like receptor, subfamily A, member 6
Klra1 killer cell lectin-like receptor, subfamily A, member 1
Klra3 killer cell lectin-like receptor, subfamily A, member 3
Klra2 killer cell lectin-like receptor, subfamily A, member 2
Sequences
M25812 (GenBank | EMBL | ENA | DDBJ | MGI Sequence Detail)
Polymorphisms
J:10723 Yokoyama WM, et al., J Immunol. 1990 Oct 1;145(7):2353-8
Notes: A 639bp PstI fragment was used for hybridization.
Endonuclease Gene Allele Fragments Strains
HindIII Klra a multiple A/J, AKR/J, BALB/c, C3H/HeJ, CBA/J, DBA/2J
b multiple B10.A-H2a, B10.A-H2h4/(4R), B10.A-H2i3/(3R), B10.A-H2i5/(R5)SgSn, C57BL/6
c multiple C57BR/cdJ, C57L/J, SJL/J
d multiple SWR
e multiple NZB, NZW
J:27399 Scalzo AA, et al., Genomics. 1995 Jun 10;27(3):435-41
Notes: A 639bp PstI fragment of pA1.3 was used to probe Southerns.
Endonuclease Gene Allele Fragments Strains
HindIII Klra b 6.6,6.4kb C57BL/6J
c absent BALB/cJ
References
J:16721 Yokoyama WM, et al., A murine T lymphocyte antigen belongs to a supergene family of type II integral membrane proteins. J Immunol. 1989 Aug 15;143(4):1379-86
J:10723 Yokoyama WM, et al., Chromosomal location of the Ly-49 (A1, YE1/48) multigene family. Genetic association with the NK 1.1 antigen. J Immunol. 1990 Oct 1;145(7):2353-8
J:27399 Scalzo AA, et al., Genetic mapping of Cmv1 in the region of mouse chromosome 6 encoding the NK gene complex-associated loci Ly49 and musNKR-P1. Genomics. 1995 Jun 10;27(3):435-41
J:49203 Smith KM, et al., Ly-49D and Ly-49H associate with mouse DAP12 and form activating receptors. J Immunol. 1998 Jul 1;161(1):7-10
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/17/2024
MGI 6.24 		The Jackson Laboratory