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Tnfa cDNA1 Probe Detail
Nucleotide
Probe/Clone
  • Name
    Tnfa cDNA1
  • Sequence Type
    cDNA
  • ID
    MGI:18959
  • Region Covered
    5' untranslated, coding region, 3' untranslated
  • Insert Size
    1.1kb
Source
  • Species
    mouse, laboratory
  • Tissue
    macrophage
Genes
Tnf tumor necrosis factor
Polymorphisms
J:17645 Vincek V, et al., Cancer Res. 1993 Feb 15;53(4):728-32
Notes: The 12kb BamHI band is cDNA from UVB light resistant strains, wheras the 10.5kb BamHI band is from UVB light susceptible strains.
Endonuclease Gene Allele Fragments Strains
BamHI Tnf c 12.0kb A.SW-H2s/Sn, B10.BR-H2k, B10.M-H2f/Sn, B10.Q-H2q/SgJ, B10.S-H2s/J, C3H/HeJ, C3H/HeN, C57BL/10
s 10.5kb A.TH-H2t2, A/J, B10.A-H2a, B10.D2-H2d, B10.D2-H2ia/(106R)EgJ, B10.T-H2y2/(6R), BALB/c, DBA/2J, P/J, SJL/J
J:17343 Richardson JC, et al., Mouse Genome. 1994;92(1):133-34
Endonuclease Gene Allele Fragments Strains
BamHI Tnf a 10.5kb A.AL-H2a1, B10.D2-H2i7/(107R)EgJ, B10.DR2, B10.HTT-H2t3, B10.M-H2ap1/(11R), B10.S-H2t2/(7R), B10.TFR5, MA.R3, MA.R4
b 12.0kb B6.AKL, B10.A-H2h2/(2R), B10.AKM-H2m/SnJ, B10.BYR-H2by1, B10.D2-H2g1(R101), B10.D2-H2g3/(103R)EgJ, B10.M-H2aq1/(17R), B10.MR1, B10.OH-H2o2, B10.RIII-H2r/(20R), B10.RIII-H2r/Sn, B10.TFRI, B10.WB-H2ja/Sn, BALB.HTG-H2g
References
J:1314 Lafuse WP, et al., PFGE mapping and RFLP analysis of the S/D region of the mouse H-2 complex. Immunogenetics. 1992;36(2):110-6
J:17645 Vincek V, et al., Tumor necrosis factor alpha polymorphism correlates with deleterious effects of ultraviolet B light on cutaneous immunity. Cancer Res. 1993 Feb 15;53(4):728-32
J:17343 Richardson JC, et al., Restriction fragment length polymorphism of tumor necrosis factor alpha in H-2 congenic inbred strains. Mouse Genome. 1994;92(1):133-34

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory