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lambda-8.1 Probe Detail
Nucleotide
Probe/Clone
  • Name
    lambda-8.1
  • Sequence Type
    cDNA
  • ID
    MGI:19517
  • Region Covered
    5' untranslated, entire coding region, 3' untranslated; corresponding to necleotides 1410-1812 of Nramp
  • Vector Type
    Phage
  • Insert Size
    ~2.2kb
  • Note
    This clone is derived from a gene that produces alternate transcripts.
Source
  • Species
    mouse, laboratory
  • Strain
    B10.L-Slc11a1
  • Tissue
    macrophage
  • Cell Line
    B10.L-Lsh
Genes
Slc11a1-rs1 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1, related sequence 1
Slc11a1 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1
Sequences
Polymorphisms
J:19177 Dosik JK, et al., Mamm Genome. 1994 Jul;5(7):458-60
Notes: A 1.9kb fragment of [l]8.1 was used as a hybridization probe on Southerns.
Endonuclease Gene Allele Fragments Strains
SstI Slc11a1 c not given BALB/cAnPt
s 2.5kb M. spretus
SstI Slc11a1-rs1 c 6.3,5.0,4.8,3.0kb BALB/cAnPt
s 3.8kb M. spretus
TaqI Slc11a1-rs1 c 9.4kb BALB/cAnPt
d 15.0kb DBA/2N
References
J:17877 Barton CH, et al., NH2-terminal sequence of macrophage-expressed natural resistance-associated macrophage protein (Nramp) encodes a proline/serine-rich putative Src homology 3-binding domain. J Exp Med. 1994 May 1;179(5):1683-7
J:19177 Dosik JK, et al., An Nramp-related sequence maps to mouse chromosome 17. Mamm Genome. 1994 Jul;5(7):458-60

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory