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Pax2 cDNA3 Probe Detail
Nucleotide
Probe/Clone
  • Name
    Pax2 cDNA3
  • Sequence Type
    cDNA
  • ID
    MGI:21330
  • Region Covered
    sequence downstream from the paired box sequence
  • Parent Clone
  • Vector Type
    Plasmid
  • Insert Site
    BamHI/EcoRI
  • Insert Size
    0.53kb
  • Note
    This clone is derived from a gene that produces alternate transcripts.
Source
  • Species
    mouse, laboratory
  • Age
    embryonic day 12.5
  • Tissue
    embryo
Genes
Pax2 paired box 2
Expression
  • Assay Results
    475
References
J:72 Plachov D, et al., Pax8, a murine paired box gene expressed in the developing excretory system and thyroid gland. Development. 1990 Oct;110(2):643-51
J:10797 Dressler GR, et al., Pax2, a new murine paired-box-containing gene and its expression in the developing excretory system. Development. 1990 Aug;109(4):787-95
J:20056 Nornes HO, et al., Spatially and temporally restricted expression of Pax2 during murine neurogenesis. Development. 1990 Aug;109(4):797-809
J:1912 Dressler GR, et al., Pax-2 is a DNA-binding protein expressed in embryonic kidney and Wilms tumor. Proc Natl Acad Sci U S A. 1992 Feb 15;89(4):1179-83
J:3679 Asano M, et al., Pax-5 is expressed at the midbrain-hindbrain boundary during mouse development. Mech Dev. 1992 Nov;39(1-2):29-39
J:12768 Fickenscher HR, et al., Murine Pax-2 protein is a sequence-specific trans-activator with expression in the genital system. DNA Cell Biol. 1993 Jun;12(5):381-91
J:21884 Stark K, et al., Epithelial transformation of metanephric mesenchyme in the developing kidney regulated by Wnt-4. Nature. 1994 Dec 15;372(6507):679-83
J:27755 Rowitch DH, et al., Pax-2 expression in the murine neural plate precedes and encompasses the expression domains of Wnt-1 and En-1. Mech Dev. 1995 Jul;52(1):3-8
J:30343 Torres M, et al., Pax-2 controls multiple steps of urogenital development. Development. 1995 Dec;121(12):4057-65
J:36834 Torres M, et al., Pax2 contributes to inner ear patterning and optic nerve trajectory. Development. 1996 Nov;122(11):3381-91
J:40605 Miyamoto N, et al., Defects of urogenital development in mice lacking Emx2. Development. 1997 May;124(9):1653-64
J:41809 Filosa S, et al., goosecoid and HNF-3 beta genetically interact to regulate neural tube patterning during mouse embryogenesis. Development. 1997 JUL;124(14):2843-2854
J:43464 Matise MP, et al., Expression patterns of developmental control genes in normal and Engrailed-1 mutant mouse spinal cord reveal early diversity in developing interneurons. J Neurosci. 1997 Oct 15;17(20):7805-16
J:45075 Schwarz M, et al., Conserved biological function between Pax-2 and Pax-5 in midbrain and cerebellum development: evidence from targeted mutations. Proc Natl Acad Sci U S A. 1997 Dec 23;94(26):14518-23
J:45681 Suda Y, et al., Cooperation between Otx1 and Otx2 genes in developmental patterning of rostral brain. Mech Dev. 1997 Dec;69(1-2):125-41
J:46638 Cho EA, et al., Differential expression and function of cadherin-6 during renal epithelium development. Development. 1998 Mar;125(5):803-12
J:46641 Rhinn M, et al., Sequential roles for Otx2 in visceral endoderm and neuroectoderm for forebrain and midbrain induction and specification. Development. 1998 Mar;125(5):845-56
J:51693 Grimm C, et al., Aphakia (ak), a mouse mutation affecting early eye development: fine mapping, consideration of candidate genes and altered Pax6 and Six3 gene expression pattern. Dev Genet. 1998;23(4):299-316
J:51989 Suda Y, et al., Functional equivalency between Otx2 and Otx1 in development of the rostral head. Development. 1999 Feb;126(4):743-57
J:52599 Mendelsohn C, et al., Stromal cells mediate retinoid-dependent functions essential for renal development. Development. 1999 Mar;126(6):1139-48
J:54493 Donovan MJ, et al., Initial differentiation of the metanephric mesenchyme is independent of WT1 and the ureteric bud. Dev Genet. 1999;24(3-4):252-62
J:58307 Rowitch DH, et al., Pax-2 regulatory sequences that direct transgene expression in the developing neural plate and external granule cell layer of the cerebellum. Brain Res Dev Brain Res. 1999 Oct 20;117(1):99-108
J:64590 Schwarz M, et al., Spatial specification of mammalian eye territories by reciprocal transcriptional repression of pax2 and pax6. Development. 2000 Oct;127(20):4325-34
J:67157 McCright B, et al., Defects in development of the kidney, heart and eye vasculature in mice homozygous for a hypomorphic Notch2 mutation. Development. 2001 Feb;128(4):491-502
J:70745 Suda Y, et al., Emx2 directs the development of diencephalon in cooperation with Otx2. Development. 2001 Jul;128(13):2433-50
J:70836 Romand R, et al., Specific expression of the retinoic acid-synthesizing enzyme RALDH2 during mouse inner ear development. Mech Dev. 2001 Aug;106(1-2):185-9
J:73067 Li JY, et al., Otx2 and Gbx2 are required for refinement and not induction of mid-hindbrain gene expression. Development. 2001 Dec;128(24):4979-91
J:74241 Barbieri AM, et al., Vax2 inactivation in mouse determines alteration of the eye dorsal-ventral axis, misrouting of the optic fibres and eye coloboma. Development. 2002 Feb;129(3):805-13
J:75950 Mic FA, et al., Novel retinoic acid generating activities in the neural tube and heart identified by conditional rescue of Raldh2 null mutant mice. Development. 2002 May;129(9):2271-82
J:80177 Aoto K, et al., Mouse GLI3 Regulates Fgf8 Expression and Apoptosis in the Developing Neural Tube, Face, and Limb Bud. Dev Biol. 2002 Nov 15;251(2):320-32
J:83255 Chi CL, et al., The isthmic organizer signal FGF8 is required for cell survival in the prospective midbrain and cerebellum. Development. 2003 Jun;130(12):2633-44
J:83659 Wright TJ, et al., Fgf3 and Fgf10 are required for mouse otic placode induction. Development. 2003 Aug;130(15):3379-90
J:86839 Liguori GL, et al., Anterior neural plate regionalization in cripto null mutant mouse embryos in the absence of node and primitive streak. Dev Biol. 2003 Dec 15;264(2):537-49
J:87221 Alvarez Y, et al., Requirements for FGF3 and FGF10 during inner ear formation. Development. 2003 Dec;130(25):6329-38
J:89365 Cecconi F, et al., Apaf1-dependent programmed cell death is required for inner ear morphogenesis and growth. Development. 2004 May;131(9):2125-35
J:90407 Wright TJ, et al., Mouse FGF15 is the ortholog of human and chick FGF19, but is not uniquely required for otic induction. Dev Biol. 2004 May 1;269(1):264-75
J:91443 Wilm B, et al., The forkhead genes, Foxc1 and Foxc2, regulate paraxial versus intermediate mesoderm cell fate. Dev Biol. 2004 Jul 1;271(1):176-89
J:93088 Landgren H, et al., FoxJ3, a novel mammalian forkhead gene expressed in neuroectoderm, neural crest, and myotome. Dev Dyn. 2004 Oct;231(2):396-401
J:108109 Oxburgh L, et al., TGFbeta superfamily signals are required for morphogenesis of the kidney mesenchyme progenitor population. Development. 2004 Sep;131(18):4593-605
J:108393 Chung AC, et al., Loss of orphan nuclear receptor GCNF function disrupts forebrain development and the establishment of the isthmic organizer. Dev Biol. 2006 May 1;293(1):13-24
J:119875 Lebel M, et al., Gli2 and Gli3 play distinct roles in the dorsoventral patterning of the mouse hindbrain. Dev Biol. 2007 Feb 1;302(1):345-55
J:153561 Dominguez-Frutos E, et al., Tissue-specific requirements for FGF8 during early inner ear development. Mech Dev. 2009 Oct;126(10):873-81
J:163739 Leung AW, et al., Loss of procollagen IIA from the anterior mesendoderm disrupts the development of mouse embryonic forebrain. Dev Dyn. 2010 Sep;239(9):2319-29
J:177278 Chang SL, et al., Region- and cell type-selective expression of the evolutionarily conserved Nolz-1/zfp503 gene in the developing mouse hindbrain. Gene Expr Patterns. 2011 Dec;11(8):525-32
J:206883 Murashima A, et al., Midline-derived Shh regulates mesonephric tubule formation through the paraxial mesoderm. Dev Biol. 2014 Feb 1;386(1):216-26
J:208898 Huang CC, et al., Lhx1 is required in Mullerian duct epithelium for uterine development. Dev Biol. 2014 May 15;389(2):124-36
J:327588 Yamada R, et al., Single-cell transcriptional analysis reveals developmental stage-dependent changes in retinal progenitors in the murine early optic vesicle. Biochem Biophys Res Commun. 2021 Mar 5;543:80-86

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
06/12/2024
MGI 6.13
The Jackson Laboratory