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Gabrg2-primer1,Gabrg2-primer2 Primer Detail
Primers
  • Name
    Gabrg2-primer1,Gabrg2-primer2
  • Primer 1 Sequence
    TTGGGTACCTCTTCTGCAACCCAGAGGCGAG
  • Primer 2 Sequence
    GTTGGATCCCACATTCGGTGACCACACATAGG
  • ID
    MGI:2152317
  • Region Covered
    coding region of Gabrg2
Genes
Gabrg2 gamma-aminobutyric acid type A receptor, subunit gamma 2
Polymorphisms
J:67847 Buck KJ, et al., Mamm Genome. 1998 Dec;9(12):975-8
Notes: Sequence comparison of the Gabr2g coding region between DBA/2J and C57BL/6J revealed 2 silent mutations (GGC vs GGG at glycine residue 37; ACG vs ACT at threonine residue 210) and one missense mutation (ACT vs GCT at residue 11, threonine vs alanine), respectively. Gabrg2 is a likely candidate gene for the alcohol withdrawal QTL on mouse chromosome 11, Alcw3.
Endonuclease Gene Allele Fragments Strains
Gabrg2 b not given C57BL/6J
d not given DBA/2J
References
J:67847 Buck KJ, et al., Genetic association of a GABA(A) receptor gamma2 subunit variant with severity of acute physiological dependence on alcohol. Mamm Genome. 1998 Dec;9(12):975-8
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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08/02/2024
MGI 6.24 		The Jackson Laboratory