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Scx cDNA Probe Detail
Nucleotide
Probe/Clone
  • Name
    Scx cDNA
  • Sequence Type
    cDNA
  • ID
    MGI:24254
  • Region Covered
    162bp of 5' untranslated, entire coding region, 297bp of 3' noncoding
  • Insert Size
    1.14kb
  • Note
    Represents several overlapping Scx cDNA clones.
Source
  • Species
    mouse, laboratory
  • Age
    embryonic day 13.0
  • Tissue
    embryo
Genes
Scx scleraxis scleraxis bHLH transcription factor
Expression
  • Assay Results
    25
Sequences
S78079 (GenBank | EMBL | ENA | DDBJ | MGI Sequence Detail)
Polymorphisms
J:24330 Cserjesi P, et al., Development. 1995 Apr;121(4):1099-110
Notes: A ~600bp StuI/NotI fragment of Scx cDNA was used in Southern analysis.
Endonuclease Gene Allele Fragments Strains
EcoRI Scx b 10.1,2.5kb C57BL/6J
s 6.0,2.5kb M. spretus
References
J:24330 Cserjesi P, et al., Scleraxis: a basic helix-loop-helix protein that prefigures skeletal formation during mouse embryogenesis. Development. 1995 Apr;121(4):1099-110
J:24364 Burgess R, et al., Paraxis: a basic helix-loop-helix protein expressed in paraxial mesoderm and developing somites. Dev Biol. 1995 Apr;168(2):296-306
J:62022 Leitges M, et al., The paired homeobox gene Uncx4.1 specifies pedicles, transverse processes and proximal ribs of the vertebral column. Development. 2000 Jun;127(11):2259-67
J:71745 Schweitzer R, et al., Analysis of the tendon cell fate using Scleraxis, a specific marker for tendons and ligaments. Development. 2001 Oct;128(19):3855-66
J:139636 Grifone R, et al., Properties of branchiomeric and somite-derived muscle development in Tbx1 mutant embryos. Dev Dyn. 2008 Sep 24;237(10):3071-3078
J:309563 Rafipay A, et al., Knockdown of slit signaling during limb development leads to a reduction in humerus length. Dev Dyn. 2021 Sep;250(9):1340-1357
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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11/12/2024
MGI 6.24 		The Jackson Laboratory