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Nkx-2.5a Probe Detail
Nucleotide
Probe/Clone
  • Name
    Nkx-2.5a
  • Sequence Type
    cDNA
  • ID
    MGI:8984
  • Region Covered
    5' untranslated region (275bp), entire coding region (957bp) and partial 3' untranslated region (364bp)
  • Child Clone
    Nkx-2.5 probe
  • Vector Type
    Plasmid
  • Insert Size
    1.6kb
Source
  • Species
    mouse, laboratory
  • Tissue
    heart
Genes
Nkx2-5 NK2 homeobox 5
Polymorphisms
J:22185 Himmelbauer H, et al., Mamm Genome. 1994 Dec;5(12):814-6
Notes: A 1.3kb EcoRI fragment was used as the hybridization probe.
Endonuclease Gene Allele Fragments Strains
BglII Nkx2-5 b 3.8,3.6kb 129X1/SvJ, C57BL/6J
d 3.0kb STOCK tw2/tw2
HincII Nkx2-5 b absent C57BL/6J
s 3.7kb M. spretus
TaqI Nkx2-5 b not given C57BL/6J
c not given M. m. castaneus
References
J:15282 Lints TJ, et al., Nkx-2.5: a novel murine homeobox gene expressed in early heart progenitor cells and their myogenic descendants [published erratum appears in Development 1993 Nov;119(3):969]. Development. 1993 Oct;119(2):419-31
J:22185 Himmelbauer H, et al., High-resolution genetic analysis of a deletion on mouse chromosome 17 extending over the fused, tufted, and homeobox Nkx2-5 loci. Mamm Genome. 1994 Dec;5(12):814-6
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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11/12/2024
MGI 6.24 		The Jackson Laboratory