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Tcrg cDNA Probe Detail
Nucleotide
Probe/Clone
  • Name
    Tcrg cDNA
  • Sequence Type
    cDNA
  • ID
    MGI:9644
  • Region Covered
    encodes gene segments Tcrg-V2, J2, and C2
  • Insert Size
    700 bp
  • Note
    The nomenclature used here to describe the Tcrg gene segments is suggested by S. Tonegawa. For more information, see Takagaki (1989), J Immunol 142:2112-2121.
Source
  • Species
    mouse, laboratory
  • Tissue
    T-lymphocyte
  • Cell Line
    MD26
Genes
Tcrg T cell receptor gamma chain
Tcrg-C T cell receptor gamma, constant region
Tcrg-J T cell receptor gamma, joining region
Trgv2 T cell receptor gamma variable 2
Polymorphisms
J:8329 Owen FL, et al., J Immunol. 1986 Aug 1;137(3):1044-6
Notes: Southern analysis using PstI and EcoRI distinquish C57BL/6J, BALB/cJ and C3H/HeJ from DBA/2J.
Endonuclease Gene Allele Fragments Strains
BamHI Tcrg b not given BALB/cJ
c not given AKR/J
BglI Tcrg b not given BALB/cJ
c not given AKR/J
EcoRV Tcrg a 11,9,7.5kb C3H/HeJ, C58/J, CBA/J, CE/J, DBA/2J, LG/J, MA/MyJ, PL/J, RIIIS/J, SM/J
b 25,16.5,9,7.5,6.2kb BALB/cJ, C57BL/6J, C57BR/cdJ, C57L/J, C.AL-20/AnN, RF/J
c not given AKR/J, LP/J, NZB/BlNJ, P/J, ST/bJ, SWR/J
d not given I/LnJ
e not given 129P3/J, A/J
HindIII Tcrg b not given BALB/cJ
c not given AKR/J
KpnI Tcrg b not given BALB/cJ
c not given AKR/J
J:9122 Holcombe RF, et al., Genomics. 1987 Nov;1(3):287-91
Endonuclease Gene Allele Fragments Strains
Not Specified Tcrg a not given C3H/HeJ
b not given B6.C3Rl-Lystbg
References
J:7996 Murre C, et al., Human gamma-chain genes are rearranged in leukaemic T cells and map to the short arm of chromosome 7. Nature. 1985 Aug 8-14;316(6028):549-52
J:8329 Owen FL, et al., The murine gamma-chain of the T cell receptor is closely linked to a spermatocyte specific histone gene and the beige coat color locus on chromosome 13. J Immunol. 1986 Aug 1;137(3):1044-6
J:9122 Holcombe RF, et al., Relationship of the genes for Chediak-Higashi syndrome (beige) and the T-cell receptor gamma chain in mouse and man. Genomics. 1987 Nov;1(3):287-91
J:3881 Johnson KR, et al., Identification and genetic mapping of the murine gene and 20 related sequences encoding chromosomal protein HMG-17. Mamm Genome. 1993;4(2):83-9
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/10/2024
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