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T105 Probe Detail
Nucleotide
Probe/Clone
  • Name
    T105
  • Sequence Type
    genomic
  • ID
    MGI:9676
  • Insert Size
    3.7 kb
Source
  • Species
    mouse, laboratory
  • Strain
    BALB/c
Genes
Igkc immunoglobulin kappa constant
Igk-V1 immunoglobulin kappa chain variable 1 (V1)
Polymorphisms
J:8073 Dzierzak EA, et al., J Exp Med. 1985 Nov 1;162(5):1494-511
Notes: A fragment encoding sequence 5' of the coding region was derived from T105 and used in Southern analysis. The 8.5 kb band in BALB/c and the 5.5 kb band in C.C58 are derived from the VK1c gene segment. The 6.0 kb band in BALB/c is derived from the VK1a gene segment.
Endonuclease Gene Allele Fragments Strains
BamHI Igk-V1 b 8.5,6.0kb BALB/c
c 5.5kb C.C58
J:8200 Dzierzak EA, et al., J Immunol. 1986 Mar 1;136(5):1864-70
Notes: A 1.1 kb HindIII fragment encoding sequence 5' of the coding region was derived from T105 and used in Southern analysis. The 8.5 kb band in BALB/c and the 5.5 kb band in C.C58 are derived from the VK1c gene segment. The 6.0 kb band in BALB/c is derivedfrom the VK1a gene segment.
Endonuclease Gene Allele Fragments Strains
BamHI Igk-V1 b 8.5,6.0kb BALB/c
c 5.5kb C.C58
J:9339 D'Hoostelaere L, et al., Curr Top Microbiol Immunol. 1988;137:116-29
Endonuclease Gene Allele Fragments Strains
HindIII Igk-V1 a 10,7,6.7,6.6,3kb AKR, PL
b 10,9.0,7,6.7,3kb C58, CE, NZB
c 10,6.7,6.6,3kb BALB/c, C57BL/6, SJL
d not given O20
References
J:8073 Dzierzak EA, et al., Molecular characterization of antibodies bearing Id-460. II. Molecular basis for Id-460 expression. J Exp Med. 1985 Nov 1;162(5):1494-511
J:8200 Dzierzak EA, et al., Molecular characterization of antibodies bearing Id-460. I. The structure of two highly homologous VH genes used to produce idiotype positive immunoglobulins. J Immunol. 1986 Mar 1;136(5):1864-70
J:9339 D'Hoostelaere L, et al., The organization of the immunoglobulin kappa locus in mice. Curr Top Microbiol Immunol. 1988;137:116-29
J:10769 D'Hoostelaere LA, et al., Characterization of new mouse V kappa groups. J Immunol. 1990 Oct 15;145(8):2706-12
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/10/2024
MGI 6.24 		The Jackson Laboratory