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pSC25 Probe Detail
Nucleotide
Probe/Clone
  • Name
    pSC25
  • Sequence Type
    cDNA
  • ID
    MGI:9879
Source
  • Species
    mouse, laboratory
  • Tissue
    brain
Genes
D5Mnl25e DNA segment, Chr 5, Massachusetts Neurogenetics Laboratory 25, expressed
Polymorphisms
J:9505 Geissler EN, et al., Proc Natl Acad Sci U S A. 1988 Dec;85(24):9635-9
Notes: A 0.4kb EcoRI/HincII fragment was used for Southern blot analysis.
Endonuclease Gene Allele Fragments Strains
AluI D5Mnl25e b 0.8kb C57BL/6J
h 0.6kb C3H/HeJ
TaqI D5Mnl25e d not given M. m. domesticus
h ~4.0kb C3H/HeJ
s ~3.5kb M. spretus
J:9764 Cheng SV, et al., Genomics. 1989 Apr;4(3):419-26
Endonuclease Gene Allele Fragments Strains
BglII D5Mnl25e a 14.0kb AKR/J, BALB/cByJ
d 10.0,3.4kb C3H/HeJ, DBA/2J
MspI D5Mnl25e a 8.7,4.1,2.4kb BALB/cByJ
d 8.7,4.1,2.9,1.3kb C3H/HeJ
XamI D5Mnl25e b 1.5kb C57BL/6J
s 2.4kb M. spretus
XmnI D5Mnl25e a 1.4kb AKR/J, BALB/cByJ
d 2.1kb C3H/HeJ, DBA/2J
J:19185 Grosson CL, et al., Mamm Genome. 1994 Jul;5(7):424-8
Notes: A 0.43kb EcoRI/HincII fragment of pSC25 was used for Southern hybridization.
Endonuclease Gene Allele Fragments Strains
XmnI D5Mnl25e b 1.7kb C57BL/6
c 2.4kb CBA
s 2.6kb M. spretus
References
J:9505 Geissler EN, et al., Genetic analysis of the dominant white-spotting (W) region on mouse chromosome 5: identification of cloned DNA markers near W. Proc Natl Acad Sci U S A. 1988 Dec;85(24):9635-9
J:9764 Cheng SV, et al., Synteny on mouse chromosome 5 of homologs for human DNA loci linked to the Huntington disease gene. Genomics. 1989 Apr;4(3):419-26
J:19185 Grosson CL, et al., Synteny conservation of the Huntington's disease gene and surrounding loci on mouse Chromosome 5. Mamm Genome. 1994 Jul;5(7):424-8
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory