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probe 3 Probe Detail
Nucleotide
Probe/Clone
  • Name
    probe 3
  • Sequence Type
    genomic
  • ID
    MGI:9977
  • Region Covered
    encodes a 5' portion of H-2Eb
  • Parent Clone
  • Insert Site
    EcoRI
  • Insert Size
    2.0kb
  • Note
    The authors say this clone contains a 1.8kb fragment of the gene.
Source
  • Species
    mouse, laboratory
  • Strain
    BALB/c
  • Tissue
    sperm
Genes
H2-Eb1 histocompatibility 2, class II antigen E beta
Polymorphisms
J:6885 Steinmetz M, et al., Nature. 1982 Nov 4;300(5887):35-42
Endonuclease Gene Allele Fragments Strains
BamHI H2-Eb1 a 6.2kb A, B10.M-H2ap1/(11R)
b 8.2kb A.SW-H2s/Sn, B10.Q-H2q/SgJ, C57BL/6
c 4.8kb B10.D2-H2d, BALB/c
EcoRI H2-Eb1 b 15.0kb B10.M-H2ap1/(11R)
c 2.0kb A, A.SW-H2s/Sn, B10.Q-H2q/SgJ, BALB/c, C57BL/6
KpnI H2-Eb1 a 24.6kb A.SW-H2s/Sn
b 9.6kb B10.A-H2i3/(3R), B10.A-H2i5/(R5)SgSn, C57BL/6
c 16.7kb A, B10.A-H2h4/(4R), BALB/c, C3H
J:7675 Shin HS, et al., Cell. 1984 Dec;39(3 Pt 2):573-8
Notes: Strain and/or t haplotype designations appear in the allele groupings.
Endonuclease Gene Allele Fragments Strains
BamHI H2-Eb1 a 12.0kb C3.t12, C3H, STOCK tw32
b 11.0kb C3.tw5
J:20596 Koide Y, et al., Tohoku J Exp Med. 1994 May;173(1):157-70
Endonuclease Gene Allele Fragments Strains
BamHI H2-Eb1 b 13.0kb C57BL/6, CTS, ILI, NOD
c 5.5kb BALB/c
n 4.8kb NON
EcoRI H2-Eb1 b 2.1kb C57BL/6, CTS, ILI, NOD, NON
c 1.9kb BALB/c
HindIII H2-Eb1 b 8.0kb BALB/c, C57BL/6, CTS, ILI, NOD
n 3.1kb NON
KpnI H2-Eb1 b 10.5kb C57BL/6
c 15.0kb BALB/c, NON
i 23.5kb CTS, ILI, NOD
References
J:6885 Steinmetz M, et al., A molecular map of the immune response region from the major histocompatibility complex of the mouse. Nature. 1982 Nov 4;300(5887):35-42
J:7675 Shin HS, et al., Gene mapping within the T/t complex of the mouse. IV: The inverted MHC is intermingled with several t-lethal genes. Cell. 1984 Dec;39(3 Pt 2):573-8
J:20596 Koide Y, et al., Molecular analysis of the pathogenesis of autoimmune insulitis in NOD mice. Tohoku J Exp Med. 1994 May;173(1):157-70

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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory