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Wt1tm2(cre/ERT2)Wtp - Cavities & Their Linings
Recombinase Activity Detail
Allele Information
Allele:
Wt1tm2(cre/ERT2)Wtp
WT1 transcription factor; targeted mutation 2, William T Pu 		Driver: Wt1
Type: Targeted (Inducible, Recombinase)
Inducer: tamoxifen
Synonym: Wt1CreERT2, Wt1iCre, Wt1tm2(cre/ESR1)Wtp
Molecular description: Exon 1 was replaced with an inducible cre ESR1 (ERT2) fusion followed by an FRT-flanked neo cassette. Testing in 2023 by the investigator's laboratory, indicates that the FRT-flanked neo has not been removed as reported.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Wt1tm2(cre/ERT2)Wtp activity also observed in:
cardiovascular system, muscle, respiratory system
Tissue Information
Cavities & Their Linings Other recombinase alleles with activity in Cavities & Their Linings tissues:
Recombinase Activity
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Assays Genotypic Background Result Notes  
Cell Type
Assay Type
Reporter Gene
Detection Method
Assay Note
Allelic Composition, Genetic Background
Sex
Specimen Notes
Result Note
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References
All for this allele: 89 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory
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