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Sequence Detail
ID/Version
A1KXC4 A1KXC8 Q148B9 Q9D8T1 A1KXC9 A1KXC6 (UniProt | EBI) Last sequence update: 2007-04-17
Last annotation update: 2024-07-24
Sequence
description
from provider
RecName: Full=Immunoglobulin mu Fc receptor {ECO:0000250|UniProtKB:O60667}; Short=IgM FcR {ECO:0000250|UniProtKB:O60667};AltName: Full=Fas apoptotic inhibitory molecule 3 {ECO:0000250|UniProtKB:O60667}; Short=FAIM3 {ECO:0000303|PubMed:3478
Provider SWISS-PROT
Sequence
Polypeptide 422 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Fcmr Fc fragment of IgM receptor 29 96 2 15
Sequence references in MGI J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:190113 Ouchida R, et al., Critical role of the IgM Fc receptor in IgM homeostasis, B-cell survival, and humoral immune responses. Proc Natl Acad Sci U S A. 2012 Oct 2;109(40):E2699-706
J:192603 Choi SC, et al., Mouse IgM Fc Receptor, FCMR, Promotes B Cell Development and Modulates Antigen-Driven Immune Responses. J Immunol. 2013 Feb 1;190(3):987-96
J:240689 Nguyen TT, et al., The IgM receptor FcmuR limits tonic BCR signaling by regulating expression of the IgM BCR. Nat Immunol. 2017 Mar;18(3):321-333
J:262882 Yu J, et al., Surface receptor Toso controls B cell-mediated regulation of T cell immunity. J Clin Invest. 2018 May 1;128(5):1820-1836
J:340662 Rochereau N, et al., Essential role of TOSO/FAIM3 in intestinal IgM reverse transcytosis. Cell Rep. 2021 Nov 16;37(7):110006

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory