Sequence Detail

ID/Version

A1Y9I9 (UniProt | EBI)

Last sequence update: 2007-02-06
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Transmembrane O-methyltransferase homolog {ECO:0000305}; Short=mTOMT {ECO:0000303|PubMed:28504928}; EC=2.1.1.6 {ECO:0000269|PubMed:18794526};AltName: Full=Catechol O-methyltransferase 2 {ECO:0000303|PubMed:18794526};

Provider

SWISS-PROT

Sequence

Polypeptide 258 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Tomt	transmembrane O-methyltransferase	18	96	5	10

Sequence references in MGI

J:137493 Du X, et al., A catechol-O-methyltransferase that is essential for auditory function in mice and humans. Proc Natl Acad Sci U S A. 2008 Sep 23;105(38):14609-14
J:249939 Cunningham CL, et al., The murine catecholamine methyltransferase mTOMT is essential for mechanotransduction by cochlear hair cells. Elife. 2017 May 15;6:e24318
J:257320 Erickson T, et al., Integration of Tmc1/2 into the mechanotransduction complex in zebrafish hair cells is regulated by Transmembrane O-methyltransferase (Tomt). Elife. 2017 May 23;6:e28474