Sequence Detail

ID/Version

A2AN08 Q8C4W5 Q52KI4 Q80Y11 Q8CGE0 A2AN11 A2AN09 Q8BGB9 A2AN10 Q6PB49 Q6PFC7 Q8CHF3 Q8C3E8 A2AN07 Q8C8X7 (UniProt | EBI)

Last sequence update: 2007-02-20
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=E3 ubiquitin-protein ligase UBR4; EC=2.3.2.27 {ECO:0000269|PubMed:19008229};AltName: Full=N-recognin-4;

Provider

SWISS-PROT

Sequence

Polypeptide 5180 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Ubr4	ubiquitin protein ligase E3 component n-recognin 4	45	99	3	64

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:145887 Tasaki T, et al., The substrate recognition domains of the N-end rule pathway. J Biol Chem. 2009 Jan 16;284(3):1884-95
J:196073 Tasaki T, et al., UBR box N-recognin-4 (UBR4), an N-recognin of the N-end rule pathway, and its role in yolk sac vascular development and autophagy. Proc Natl Acad Sci U S A. 2013 Mar 5;110(10):3800-5
J:200306 DeMasi J, et al., Bovine papillomavirus E7 transformation function correlates with cellular p600 protein binding. Proc Natl Acad Sci U S A. 2005 Aug 9;102(32):11486-91
J:266925 Kim ST, et al., The N-recognin UBR4 of the N-end rule pathway is targeted to and required for the biogenesis of the early endosome. J Cell Sci. 2018 Sep 10;131(17):jcs217646
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89