Sequence Detail

ID/Version

B0V2N1 Q3TEC3 Q4JFC7 Q64503 Q64699 Q7TT17 Q5XJV4 Q3TXC9 (UniProt | EBI)

Last sequence update: 2008-04-08
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Receptor-type tyrosine-protein phosphatase S; Short=R-PTP-S; EC=3.1.3.48 {ECO:0000269|PubMed:7529177, ECO:0000305|PubMed:22027896};AltName: Full=PTPNU-3;AltName: Full=Receptor-type tyrosine-protein phosphatase sigma;

Provider

SWISS-PROT

Sequence

Polypeptide 1907 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Ptprs	protein tyrosine phosphatase receptor type S	67	111	3	18

Sequence references in MGI

J:22654 Wagner J, et al., Molecular cloning and tissue-specific RNA processing of a murine receptor-type protein tyrosine phosphatase. Eur J Biochem. 1994 Dec 15;226(3):773-82
J:53434 Elchebly M, et al., Neuroendocrine dysplasia in mice lacking protein tyrosine phosphatase sigma. Nat Genet. 1999 Mar;21(3):330-3
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:110032 Sapieha PS, et al., Receptor protein tyrosine phosphatase sigma inhibits axon regrowth in the adult injured CNS. Mol Cell Neurosci. 2005 Apr;28(4):625-35
J:153757 Shen Y, et al., PTPsigma is a receptor for chondroitin sulfate proteoglycan, an inhibitor of neural regeneration. Science. 2009 Oct 23;326(5952):592-6
J:167900 Fry EJ, et al., Corticospinal tract regeneration after spinal cord injury in receptor protein tyrosine phosphatase sigma deficient mice. Glia. 2010 Mar;58(4):423-33
J:171196 Coles CH, et al., Proteoglycan-specific molecular switch for RPTPsigma clustering and neuronal extension. Science. 2011 Apr 22;332(6028):484-8
J:186269 Horn KE, et al., Receptor protein tyrosine phosphatase sigma regulates synapse structure, function and plasticity. J Neurochem. 2012 Jul;122(1):147-61
J:191258 Dickendesher TL, et al., NgR1 and NgR3 are receptors for chondroitin sulfate proteoglycans. Nat Neurosci. 2012 May;15(5):703-12
J:233103 Bunin A, et al., Protein Tyrosine Phosphatase PTPRS Is an Inhibitory Receptor on Human and Murine Plasmacytoid Dendritic Cells. Immunity. 2015 Aug 18;43(2):277-88
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89