Sequence Detail

ID/Version

B1ARD8 A0A0A0MQG0 Q7TMF1 F6RTS1 Q3UBN9 (UniProt | EBI)

Last sequence update: 2008-04-08
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Schlafen family member 8 {ECO:0000305}; EC=3.1.-.- {ECO:0000269|PubMed:29563550};AltName: Full=Schlafen-8 {ECO:0000303|PubMed:15351786}; Short=mSLFN8 {ECO:0000303|PubMed:29563550};

Provider

SWISS-PROT

Sequence

Polypeptide 910 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Slfn8	schlafen 8	21	96	3	3

Sequence references in MGI

J:93660 Geserick P, et al., Modulation of T cell development and activation by novel members of the Schlafen (slfn) gene family harbouring an RNA helicase-like motif. Int Immunol. 2004 Oct;16(10):1535-48
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:258797 Nakagawa K, et al., Schlafen-8 is essential for lymphatic endothelial cell activation in experimental autoimmune encephalomyelitis. Int Immunol. 2018 Mar 8;30(2):69-78
J:283188 Yang JY, et al., Structure of Schlafen13 reveals a new class of tRNA/rRNA- targeting RNase engaged in translational control. Nat Commun. 2018 Mar 21;9(1):1165