Sequence Detail

ID/Version

B1AYL1 Q62467 (UniProt | EBI)

Last sequence update: 2008-04-08
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Sodium channel protein type 7 subunit alpha {ECO:0000305};AltName: Full=Nax channel {ECO:0000303|PubMed:11992118};AltName: Full=Sodium channel Nav2.3 {ECO:0000303|PubMed:7982916};

Provider

SWISS-PROT

Sequence

Polypeptide 1681 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Scn7a	sodium channel, voltage-gated, type VII, alpha	17	98	3	5

Sequence references in MGI

J:21714 Felipe A, et al., Primary structure and differential expression during development and pregnancy of a novel voltage-gated sodium channel in the mouse. J Biol Chem. 1994 Dec 2;269(48):30125-31
J:65133 Watanabe E, et al., Nav2/NaG channel is involved in control of salt-intake behavior in the CNS. J Neurosci. 2000 Oct 15;20(20):7743-51
J:109409 Hiyama TY, et al., Na(x) channel involved in CNS sodium-level sensing. Nat Neurosci. 2002 Jun;5(6):511-2
J:126489 Shimizu H, et al., Glial Nax channels control lactate signaling to neurons for brain [Na+] sensing. Neuron. 2007 Apr 5;54(1):59-72
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:321482 Sakuta H, et al., Nax signaling evoked by an increase in [Na+] in CSF induces water intake via EET-mediated TRPV4 activation. Am J Physiol Regul Integr Comp Physiol. 2016 Aug 1;311(2):R299-306