Sequence Detail

ID/Version

D3Z120 E0CZH3 (UniProt | EBI)

Last sequence update: 2011-04-05
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Forkhead box protein I3 {ECO:0000305};

Provider

SWISS-PROT

Sequence

Polypeptide 399 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Foxi3	forkhead box I3	18	104	5	10

Sequence references in MGI

J:198146 Shirokova V, et al., Expression of Foxi3 is regulated by ectodysplasin in skin appendage placodes. Dev Dyn. 2013 Jun;242(6):593-603
J:207523 Edlund RK, et al., Foxi transcription factors promote pharyngeal arch development by regulating formation of FGF signaling centers. Dev Biol. 2014 Jun 1;390(1):1-13
J:228880 Birol O, et al., The mouse Foxi3 transcription factor is necessary for the development of posterior placodes. Dev Biol. 2016 Jan 1;409(1):139-51
J:238111 Shirokova V, et al., Foxi3 Deficiency Compromises Hair Follicle Stem Cell Specification and Activation. Stem Cells. 2016 Jul;34(7):1896-908
J:239871 Jussila M, et al., Suppression of epithelial differentiation by Foxi3 is essential for molar crown patterning. Development. 2015 Nov 15;142(22):3954-63
J:279006 Hasten E, et al., Tbx1 and Foxi3 genetically interact in the pharyngeal pouch endoderm in a mouse model for 22q11.2 deletion syndrome. PLoS Genet. 2019 Aug;15(8):e1008301
J:336768 Mao K, et al., FOXI3 pathogenic variants cause one form of craniofacial microsomia. Nat Commun. 2023 Apr 11;14(1):2026
J:338262 Singh S, et al., Foxi3 transcription factor activity is mediated by a C-terminal transactivation domain and regulated by the Protein Phosphatase 2A (PP2A) complex. Sci Rep. 2018 Nov 22;8(1):17249