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Sequence Detail
ID/Version
D3Z120 E0CZH3 (UniProt | EBI) Last sequence update: 2011-04-05
Last annotation update: 2024-07-24
Sequence
description
from provider
RecName: Full=Forkhead box protein I3 {ECO:0000305};
Provider SWISS-PROT
Sequence
Polypeptide 399 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Foxi3 forkhead box I3 15 104 5 11
Sequence references in MGI J:198146 Shirokova V, et al., Expression of Foxi3 is regulated by ectodysplasin in skin appendage placodes. Dev Dyn. 2013 Jun;242(6):593-603
J:207523 Edlund RK, et al., Foxi transcription factors promote pharyngeal arch development by regulating formation of FGF signaling centers. Dev Biol. 2014 Jun 1;390(1):1-13
J:228880 Birol O, et al., The mouse Foxi3 transcription factor is necessary for the development of posterior placodes. Dev Biol. 2016 Jan 1;409(1):139-51
J:238111 Shirokova V, et al., Foxi3 Deficiency Compromises Hair Follicle Stem Cell Specification and Activation. Stem Cells. 2016 Jul;34(7):1896-908
J:239871 Jussila M, et al., Suppression of epithelial differentiation by Foxi3 is essential for molar crown patterning. Development. 2015 Nov 15;142(22):3954-63
J:279006 Hasten E, et al., Tbx1 and Foxi3 genetically interact in the pharyngeal pouch endoderm in a mouse model for 22q11.2 deletion syndrome. PLoS Genet. 2019 Aug;15(8):e1008301
J:336768 Mao K, et al., FOXI3 pathogenic variants cause one form of craniofacial microsomia. Nat Commun. 2023 Apr 11;14(1):2026
J:338262 Singh S, et al., Foxi3 transcription factor activity is mediated by a C-terminal transactivation domain and regulated by the Protein Phosphatase 2A (PP2A) complex. Sci Rep. 2018 Nov 22;8(1):17249

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory