ID/Version |
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Sequence description from provider |
RecName: Full=Piezo-type mechanosensitive ion channel component 1;AltName: Full=Protein FAM38A {ECO:0000303|PubMed:20813920}; | ||||||||||||||
Provider | SWISS-PROT | ||||||||||||||
Sequence |
Polypeptide
2547
aa
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Annotated genes and markers |
Follow the symbol links to get more information on the GO terms,
expression assays, orthologs, phenotypic alleles, and other information
for the genes or markers below.
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Sequence references in MGI |
J:143718
Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:164433 Coste B, et al., Piezo1 and Piezo2 are essential components of distinct mechanically activated cation channels. Science. 2010 Oct 1;330(6000):55-60 J:197533 Andolfo I, et al., Multiple clinical forms of dehydrated hereditary stomatocytosis arise from mutations in PIEZO1. Blood. 2013 May 9;121(19):3925-35, S1-12 J:212179 Ranade SS, et al., Piezo1, a mechanically activated ion channel, is required for vascular development in mice. Proc Natl Acad Sci U S A. 2014 Jul 15;111(28):10347-52 J:213170 Poole K, et al., Tuning Piezo ion channels to detect molecular-scale movements relevant for fine touch. Nat Commun. 2014;5:3520 J:217082 Li J, et al., Piezo1 integration of vascular architecture with physiological force. Nature. 2014 Nov 13;515(7526):279-82 J:217259 Peyronnet R, et al., Piezo1-dependent stretch-activated channels are inhibited by Polycystin-2 in renal tubular epithelial cells. EMBO Rep. 2013 Dec;14(12):1143-8 J:245270 Coste B, et al., Piezo proteins are pore-forming subunits of mechanically activated channels. Nature. 2012 Feb 19;483(7388):176-81 J:247395 Ge J, et al., Architecture of the mammalian mechanosensitive Piezo1 channel. Nature. 2015 Nov 05;527(7576):64-9 J:262981 Tsuchiya M, et al., Cell surface flip-flop of phosphatidylserine is critical for PIEZO1-mediated myotube formation. Nat Commun. 2018 May 24;9(1):2049 J:273541 Saotome K, et al., Structure of the mechanically activated ion channel Piezo1. Nature. 2018 Feb 22;554(7693):481-486 J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89 J:332299 Vaisey G, et al., Piezo1 as a force-through-membrane sensor in red blood cells. Elife. 2022 Dec 14;11 J:349395 Lee JH, et al., The Piezo channel is a mechano-sensitive complex component in the mammalian inner ear hair cell. Nat Commun. 2024 Jan 16;15(1):526 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/12/2024 MGI 6.24 |
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