Sequence Detail

ID/Version

O08573 Q99L83 O08572 Q3UKE5 (UniProt | EBI)

Last sequence update: 1997-07-01
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Galectin-9; Short=Gal-9;

Provider

SWISS-PROT

Sequence

Polypeptide 353 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Lgals9	lectin, galactose binding, soluble 9	61	106	10	22

Sequence references in MGI

J:38801 Wada J, et al., Identification and characterization of galectin-9, a novel beta-galactoside-binding mammalian lectin. J Biol Chem. 1997 Feb 28;272(9):6078-86
J:40498 Wada J, et al., Developmental regulation, expression, and apoptotic potential of galectin-9, a beta-galactoside binding lectin. J Clin Invest. 1997 May 15;99(10):2452-61
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:118146 Nagae M, et al., Crystal structure of the galectin-9 N-terminal carbohydrate recognition domain from Mus musculus reveals the basic mechanism of carbohydrate recognition. J Biol Chem. 2006 Nov 24;281(47):35884-93
J:166066 Jayaraman P, et al., Tim3 binding to galectin-9 stimulates antimicrobial immunity. J Exp Med. 2010 Oct 25;207(11):2343-54
J:173540 Bi S, et al., Galectin-9 binding to cell surface protein disulfide isomerase regulates the redox environment to enhance T-cell migration and HIV entry. Proc Natl Acad Sci U S A. 2011 Jun 28;108(26):10650-5
J:197208 Golden-Mason L, et al., Galectin-9 functionally impairs natural killer cells in humans and mice. J Virol. 2013 May;87(9):4835-45
J:222142 Heusschen R, et al., Profiling Lgals9 splice variant expression at the fetal-maternal interface: implications in normal and pathological human pregnancy. Biol Reprod. 2013 Jan;88(1):22
J:222664 Steelman AJ, et al., Astrocyte galectin-9 potentiates microglial TNF secretion. J Neuroinflammation. 2014;11:144
J:224716 Wu C, et al., Galectin-9-CD44 interaction enhances stability and function of adaptive regulatory T cells. Immunity. 2014 Aug 21;41(2):270-82
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89