Sequence Detail

ID/Version

O08580 Q3U110 B2RRU9 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Steroid hormone receptor ERR1;AltName: Full=Estrogen receptor-like 1;AltName: Full=Estrogen-related receptor alpha; Short=ERR-alpha;AltName: Full=Nuclear receptor subfamily 3 group B member 1;

Provider

SWISS-PROT

Sequence

Polypeptide 422 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Esrra	estrogen related receptor, alpha	40	126	3	13

Sequence references in MGI

J:42858 Sladek R, et al., The orphan nuclear receptor estrogen-related receptor alpha is a transcriptional regulator of the human medium-chain acyl coenzyme A dehydrogenase gene. Mol Cell Biol. 1997 Sep;17(9):5400-9
J:45614 Shigeta H, et al., The mouse estrogen receptor-related orphan receptor alpha 1: molecular cloning and estrogen responsiveness. J Mol Endocrinol. 1997 Dec;19(3):299-309
J:86433 Luo J, et al., Reduced fat mass in mice lacking orphan nuclear receptor estrogen-related receptor alpha. Mol Cell Biol. 2003 Nov;23(22):7947-56
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:162492 Wilson BJ, et al., An acetylation switch modulates the transcriptional activity of estrogen-related receptor alpha. Mol Endocrinol. 2010 Jul;24(7):1349-58
J:261053 Wang T, et al., GDF15 is a heart-derived hormone that regulates body growth. EMBO Mol Med. 2017 Aug;9(8):1150-1164
J:261824 Rossi M, et al., Extracellular signal-regulated kinase 8 (ERK8) controls estrogen-related receptor alpha (ERRalpha) cellular localization and inhibits its transcriptional activity. J Biol Chem. 2011 Mar 11;286(10):8507-22
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89