Sequence Detail

ID/Version

O08650 Q8CEB9 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Hyaluronan synthase 3; EC=2.4.1.212 {ECO:0000269|PubMed:10455188, ECO:0000269|PubMed:16014622};AltName: Full=Hyaluronate synthase 3;AltName: Full=Hyaluronic acid synthase 3; Short=HA synthase 3;

Provider

SWISS-PROT

Sequence

Polypeptide 554 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Has3	hyaluronan synthase 3	27	105	3	10

Sequence references in MGI

J:39442 Spicer AP, et al., Molecular cloning and characterization of a cDNA encoding the third putative mammalian hyaluronan synthase. J Biol Chem. 1997 Apr 4;272(14):8957-61
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:200337 Itano N, et al., Three isoforms of mammalian hyaluronan synthases have distinct enzymatic properties. J Biol Chem. 1999 Aug 27;274(35):25085-92
J:210601 Arranz AM, et al., Hyaluronan deficiency due to Has3 knock-out causes altered neuronal activity and seizures via reduction in brain extracellular space. J Neurosci. 2014 Apr 30;34(18):6164-76