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Sequence Detail
ID/Version
O08712 O70202 (UniProt | EBI) Last sequence update: 1997-07-01
Last annotation update: 2024-07-24
Sequence
description
from provider
RecName: Full=Tumor necrosis factor receptor superfamily member 11B;AltName: Full=Osteoclastogenesis inhibitory factor;AltName: Full=Osteoprotegerin;Flags: Precursor;
Provider SWISS-PROT
Sequence
Polypeptide 401 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Tnfrsf11b tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) 22 112 3 18
Sequence references in MGI J:39641 Simonet WS, et al., Osteoprotegerin: a novel secreted protein involved in the regulation of bone density. Cell. 1997 Apr 18;89(2):309-19
J:49549 Mizuno A, et al., Structure of the mouse osteoclastogenesis inhibitory factor (OCIF) gene and its expression in embryogenesis. Gene. 1998 Jul 30;215(2):339-43
J:64174 Min H, et al., Osteoprotegerin reverses osteoporosis by inhibiting endosteal osteoclasts and prevents vascular calcification by blocking a process resembling osteoclastogenesis. J Exp Med. 2000 Aug 21;192(4):463-74
J:245306 Nelson CA, et al., RANKL employs distinct binding modes to engage RANK and the osteoprotegerin decoy receptor. Structure. 2012 Nov 07;20(11):1971-82

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory