Sequence Detail

ID/Version

O08749 Q3U5W5 Q99LD3 Q3TG55 Q3UWP7 (UniProt | EBI)

Last sequence update: 2006-11-28
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Dihydrolipoyl dehydrogenase, mitochondrial; EC=1.8.1.4 {ECO:0000250|UniProtKB:P09622};AltName: Full=Dihydrolipoamide dehydrogenase;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 509 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Dld	dihydrolipoamide dehydrogenase	53	106	3	5

Sequence references in MGI

J:40147 Johnson M, et al., Characterization of the mouse dihydrolipoamide dehydrogenase (Dld) gene: genomic structure, promoter sequence, and chromosomal localization. Genomics. 1997 May 1;41(3):320-6
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:100834 Mitra K, et al., Novelty of the pyruvate metabolic enzyme dihydrolipoamide dehydrogenase in spermatozoa: correlation of its localization, tyrosine phosphorylation, and activity during sperm capacitation. J Biol Chem. 2005 Jul 8;280(27):25743-53
J:120800 Babady NE, et al., Cryptic proteolytic activity of dihydrolipoamide dehydrogenase. Proc Natl Acad Sci U S A. 2007 Apr 10;104(15):6158-63
J:196142 Rardin MJ, et al., Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways. Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6601-6
J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:343143 Hevler JF, et al., MRPS36 provides a structural link in the eukaryotic 2-oxoglutarate dehydrogenase complex. Open Biol. 2023 Mar;13(3):220363