Sequence Detail

ID/Version

O09000 Q9CRD5 (UniProt | EBI)

Last sequence update: 1998-08-01
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Nuclear receptor coactivator 3; Short=NCoA-3; EC=2.3.1.48;AltName: Full=Amplified in breast cancer-1 protein homolog; Short=AIB-1;AltName: Full=CBP-interacting protein; Short=p/CIP; Short=pCIP;AltName:

Provider

SWISS-PROT

Sequence

Polypeptide 1398 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Ncoa3	nuclear receptor coactivator 3	74	109	3	408

Sequence references in MGI

J:42181 Torchia J, et al., The transcriptional co-activator p/CIP binds CBP and mediates nuclear-receptor function [see comments]. Nature. 1997 Jun 12;387(6634):677-84
J:62724 Xu J, et al., The steroid receptor coactivator SRC-3 (p/CIP/RAC3/AIB1/ACTR/TRAM-1) is required for normal growth, puberty, female reproductive function, and mammary gland development. Proc Natl Acad Sci U S A. 2000 Jun 6;97(12):6379-84
J:64957 Chen D, et al., Regulation of transcription by a protein methyltransferase. Science. 1999 Jun 25;284(5423):2174-7
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:188268 Percharde M, et al., Ncoa3 functions as an essential Esrrb coactivator to sustain embryonic stem cell self-renewal and reprogramming. Genes Dev. 2012 Oct 15;26(20):2286-98
J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30
J:222684 Wansa KD, et al., The AF-1 domain of the orphan nuclear receptor NOR-1 mediates trans-activation, coactivator recruitment, and activation by the purine anti-metabolite 6-mercaptopurine. J Biol Chem. 2003 Jul 4;278(27):24776-90
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:306378 Guo A, et al., Immunoaffinity enrichment and mass spectrometry analysis of protein methylation. Mol Cell Proteomics. 2014 Jan;13(1):372-87