Sequence Detail

ID/Version

O09005 Q8R4H3 (UniProt | EBI)

Last sequence update: 1997-07-01
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Sphingolipid delta(4)-desaturase DES1 {ECO:0000305}; EC=1.14.19.17 {ECO:0000269|PubMed:11937514};AltName: Full=Degenerative spermatocyte homolog 1;AltName: Full=Dihydroceramide desaturase-1;AltName: Full=Retinol isomerase; EC

Provider

SWISS-PROT

Sequence

Polypeptide 323 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Degs1	delta 4-desaturase, sphingolipid 1	14	100	3	13

Sequence references in MGI

J:41881 Endo K, et al., Mdes, a mouse homolog of the Drosophila degenerative spermatocyte gene is expressed during mouse spermatogenesis. Dev Growth Differ. 1997 Jun;39(3):399-403
J:93864 Ternes P, et al., Identification and characterization of a sphingolipid delta 4-desaturase family. J Biol Chem. 2002 Jul 12;277(28):25512-8
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:287041 Kaylor JJ, et al., Identification of DES1 as a vitamin A isomerase in Muller glial cells of the retina. Nat Chem Biol. 2013 Jan;9(1):30-6
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89