Sequence Detail

ID/Version

O35185 P97289 (UniProt | EBI)

Last sequence update: 1998-01-01
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Class E basic helix-loop-helix protein 40; Short=bHLHe40;AltName: Full=Class B basic helix-loop-helix protein 2; Short=bHLHb2;AltName: Full=Differentially expressed in chondrocytes protein 1 {ECO:0000303|PubMed:30012868};

Provider

SWISS-PROT

Sequence

Polypeptide 411 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Bhlhe40	basic helix-loop-helix family, member e40	49	112	3	20

Sequence references in MGI

J:42215 Dear TN, et al., Identification of interaction partners for the basic-helix-loop-helix protein E47. Oncogene. 1997 Feb 27;14(8):891-8
J:42575 Boudjelal M, et al., Overexpression of Stra13, a novel retinoic acid-inducible gene of the basic helix-loop-helix family, inhibits mesodermal and promotes neuronal differentiation of P19 cells. Genes Dev. 1997 Aug 15;11(16):2052-65
J:87263 Kawamoto T, et al., A novel autofeedback loop of Dec1 transcription involved in circadian rhythm regulation. Biochem Biophys Res Commun. 2004 Jan 2;313(1):117-24
J:137262 Nakashima A, et al., DEC1 modulates the circadian phase of clock gene expression. Mol Cell Biol. 2008 Jun;28(12):4080-92
J:180477 Sato F, et al., Functional analysis of the basic helix-loop-helix transcription factor DEC1 in circadian regulation. Interaction with BMAL1. Eur J Biochem. 2004 Nov;271(22):4409-19
J:211246 Cho Y, et al., The basic helix-loop-helix proteins differentiated embryo chondrocyte (DEC) 1 and DEC2 function as corepressors of retinoid X receptors. Mol Pharmacol. 2009 Dec;76(6):1360-9
J:271702 Nakashima A, et al., Dec1 and CLOCK Regulate Na(+)/K(+)-ATPase beta1 Subunit Expression and Blood Pressure. Hypertension. 2018 Sep;72(3):746-754
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89