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Sequence Detail
ID/Version
O35387 Q542F8 (UniProt | EBI) Last sequence update: 1998-01-01
Last annotation update: 2024-11-27
Sequence
description
from provider
RecName: Full=HCLS1-associated protein X-1;AltName: Full=HS1-associating protein X-1; Short=HAX-1;AltName: Full=HS1-binding protein 1; Short=HSP1BP-1;
Provider SWISS-PROT
Sequence
Polypeptide 280 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Hax1 HCLS1 associated X-1 58 97 3 24
Sequence references in MGI J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:112369 Hippe A, et al., Expression and tissue distribution of mouse Hax1. Gene. 2006 Sep 1;379:116-26
J:132627 Chao JR, et al., Hax1-mediated processing of HtrA2 by Parl allows survival of lymphocytes and neurons. Nature. 2008 Mar 6;452(7183):98-102
J:175122 Gallagher AR, et al., The polycystic kidney disease protein PKD2 interacts with Hax-1, a protein associated with the actin cytoskeleton. Proc Natl Acad Sci U S A. 2000 Apr 11;97(8):4017-22
J:234410 Zhang Y, et al., Kv3.3 Channels Bind Hax-1 and Arp2/3 to Assemble a Stable Local Actin Network that Regulates Channel Gating. Cell. 2016 Apr 7;165(2):434-48
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:333168 Hirasaka K, et al., UCP3 is associated with Hax-1 in mitochondria in the presence of calcium ion. Biochem Biophys Res Commun. 2016 Mar 25;472(1):108-13

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory