Sequence Detail

ID/Version

O35627 O35628 Q3V008 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Nuclear receptor subfamily 1 group I member 3;AltName: Full=Constitutive androstane receptor; Short=CAR;AltName: Full=Orphan nuclear receptor MB67;

Provider

SWISS-PROT

Sequence

Polypeptide 358 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Nr1i3	nuclear receptor subfamily 1, group I, member 3	36	106	2	13

Sequence references in MGI

J:43027 Choi HS, et al., Differential transactivation by two isoforms of the orphan nuclear hormone receptor CAR. J Biol Chem. 1997 Sep 19;272(38):23565-71
J:57555 Choi HS, et al., A component of the 26S proteasome binds on orphan member of the nuclear hormone receptor superfamily. J Steroid Biochem Mol Biol. 1996 Jan;56(1-6 Spec No):23-30
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:126925 Hosseinpour F, et al., Overexpression of the Rho-guanine nucleotide exchange factor ECT2 inhibits nuclear translocation of nuclear receptor CAR in the mouse liver. FEBS Lett. 2007 Oct 16;581(25):4937-42
J:244975 Kriebs A, et al., Circadian repressors CRY1 and CRY2 broadly interact with nuclear receptors and modulate transcriptional activity. Proc Natl Acad Sci U S A. 2017 Aug 15;114(33):8776-8781