Sequence Detail

ID/Version

O35658 (UniProt | EBI)

Last sequence update: 1998-01-01
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Complement component 1 Q subcomponent-binding protein, mitochondrial;AltName: Full=GC1q-R protein;AltName: Full=Glycoprotein gC1qBP; Short=C1qBP;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 278 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	C1qbp	complement component 1, q subcomponent binding protein	91	101	3	26

Sequence references in MGI

J:44396 Lynch NJ, et al., Characterisation of the rat and mouse homologues of gC1qBP, a 33 kDa glycoprotein that binds to the globular 'heads' of C1q. FEBS Lett. 1997 Nov 24;418(1-2):111-4
J:138525 Heyd F, et al., Differential isoform expression and interaction with the P32 regulatory protein controls the subcellular localization of the splicing factor U2AF26. J Biol Chem. 2008 Jul 11;283(28):19636-45
J:189986 Reef S, et al., The autophagic inducer smARF interacts with and is stabilized by the mitochondrial p32 protein. Oncogene. 2007 Oct 11;26(46):6677-83
J:196101 Chowdhury AR, et al., Excessive reactive oxygen species induces apoptosis in fibroblasts: role of mitochondrially accumulated hyaluronic acid binding protein 1 (HABP1/p32/gC1qR). Exp Cell Res. 2008 Feb 1;314(3):651-67
J:196142 Rardin MJ, et al., Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways. Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6601-6
J:196232 Yagi M, et al., p32/gC1qR is indispensable for fetal development and mitochondrial translation: importance of its RNA-binding ability. Nucleic Acids Res. 2012 Oct;40(19):9717-37
J:262320 Feichtinger RG, et al., Biallelic C1QBP Mutations Cause Severe Neonatal-, Childhood-, or Later-Onset Cardiomyopathy Associated with Combined Respiratory-Chain Deficiencies. Am J Hum Genet. 2017 Oct 5;101(4):525-538
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89