Sequence Detail

ID/Version

O35696 Q4VA47 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Alpha-2,8-sialyltransferase 8B {ECO:0000305}; EC=2.4.3.- {ECO:0000269|PubMed:7875291};AltName: Full=Polysialic acid synthase;AltName: Full=Sialyltransferase 8B; Short=SIAT8-B;AltName: Full=Sialyltransferase St8Sia II;

Provider

SWISS-PROT

Sequence

Polypeptide 375 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	St8sia2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	37	108	3	7

Sequence references in MGI

J:28219 Kojima N, et al., Enzymatic activity of a developmentally regulated member of the sialyltransferase family (STX): evidence for alpha 2,8-sialyltransferase activity toward N-linked oligosaccharides. FEBS Lett. 1995 Feb 20;360(1):1-4
J:36852 Yoshida Y, et al., Genomic structure and promoter activity of the mouse polysialic acid synthase gene (mST8Sia II). Brain-specific expression from a TATA-less GC-rich sequence. J Biol Chem. 1996 Nov 22;271(47):30167-73
J:237112 Szewczyk LM, et al., ST8SIA2 promotes oligodendrocyte differentiation and the integrity of myelin and axons. Glia. 2017 Jan;65(1):34-49