Sequence Detail

ID/Version

O35730 Q3U333 Q63ZX8 Q3U242 Q4FK33 Q921Z8 (UniProt | EBI)

Last sequence update: 2006-04-04
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=E3 ubiquitin-protein ligase RING1; EC=2.3.2.27;AltName: Full=Polycomb complex protein RING1;AltName: Full=RING finger protein 1;AltName: Full=RING-type E3 ubiquitin transferase RING1 {ECO:0000305};AltName: Full=Transcription represso

Provider

SWISS-PROT

Sequence

Polypeptide 406 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Ring1	ring finger protein 1	39	106	2	4

Sequence references in MGI

J:43598 Schoorlemmer J, et al., Ring1A is a transcriptional repressor that interacts with the Polycomb-M33 protein and is expressed at rhombomere boundaries in the mouse hindbrain. EMBO J. 1997 Oct 1;16(19):5930-42
J:94519 de Napoles M, et al., Polycomb group proteins Ring1A/B link ubiquitylation of histone H2A to heritable gene silencing and X inactivation. Dev Cell. 2004 Nov;7(5):663-76
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:104662 Cao R, et al., Role of Bmi-1 and Ring1A in H2A ubiquitylation and Hox gene silencing. Mol Cell. 2005 Dec 22;20(6):845-54
J:119024 Buchwald G, et al., Structure and E3-ligase activity of the Ring-Ring complex of polycomb proteins Bmi1 and Ring1b. EMBO J. 2006 Jun 7;25(11):2465-74
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89