Sequence Detail

ID/Version

O35902 Q8CE48 Q8CB02 (UniProt | EBI)

Last sequence update: 1998-01-01
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Desmoglein-3;AltName: Full=130 kDa pemphigus vulgaris antigen homolog;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 993 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Dsg3	desmoglein 3	25	104	3	12

Sequence references in MGI

J:22181 Ishikawa H, et al., cDNA cloning and chromosomal assignment of the mouse gene for desmoglein 3 (Dsg3), the pemphigus vulgaris antigen. Mamm Genome. 1994 Dec;5(12):803-4
J:40804 Koch PJ, et al., Targeted disruption of the pemphigus vulgaris antigen (desmoglein 3) gene in mice causes loss of keratinocyte cell adhesion with a phenotype similar to pemphigus vulgaris. J Cell Biol. 1997 Jun 2;137(5):1091-102
J:50057 Koch PJ, et al., Desmoglein 3 anchors telogen hair in the follicle. J Cell Sci. 1998 Sep;111(Pt 17):2529-37
J:83879 Whittock NV, Genomic sequence analysis of the mouse desmoglein cluster reveals evidence for six distinct genes: characterization of mouse DSG4, DSG5, and DSG6. J Invest Dermatol. 2003 Jun;120(6):970-80
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:136806 Kanno M, et al., P120-catenin is a novel desmoglein 3 interacting partner: identification of the p120-catenin association site of desmoglein 3. Exp Cell Res. 2008 May 1;314(8):1683-92
J:229903 Rotzer V, et al., Desmoglein 3-Dependent Signaling Regulates Keratinocyte Migration and Wound Healing. J Invest Dermatol. 2016 Jan;136(1):301-10
J:352404 Fuchs M, et al., Plakophilin 1 but not plakophilin 3 regulates desmoglein clustering. Cell Mol Life Sci. 2019 Sep;76(17):3465-3476