Sequence Detail

ID/Version

O35942 Q3TPD7 O35959 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Serine/threonine-protein kinase Nek2; EC=2.7.11.1;AltName: Full=Never in mitosis A-related kinase 2; Short=NimA-related protein kinase 2;

Provider

SWISS-PROT

Sequence

Polypeptide 443 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Nek2	NIMA (never in mitosis gene a)-related expressed kinase 2	74	105	4	7

Sequence references in MGI

J:41081 Rhee K, et al., The NIMA-related kinase 2, Nek2, is expressed in specific stages of the meiotic cell cycle and associates with meiotic chromosomes. Development. 1997 Jun;124(11):2167-77
J:45011 Tanaka K, et al., The in vivo expression pattern of mouse Nek2, a NIMA-related kinase, indicates a role in both mitosis and meiosis. Exp Cell Res. 1997 Dec 15;237(2):264-74
J:47160 Arama E, et al., Murine NIMA-related kinases are expressed in patterns suggesting distinct functions in gametogenesis and a role in the nervous system. Oncogene. 1998 Apr 9;16(14):1813-23
J:87457 Yoo JC, et al., NIP1/XB51/NECAB3 is a potential substrate of Nek2, suggesting specific roles of Nek2 in Golgi. Exp Cell Res. 2004 Jan 15;292(2):393-402
J:90007 Di Agostino S, et al., Phosphorylation of high-mobility group protein A2 by Nek2 kinase during the first meiotic division in mouse spermatocytes. Mol Biol Cell. 2004 Mar;15(3):1224-32
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563