Sequence Detail

ID/Version

O54788 (UniProt | EBI)

Last sequence update: 1998-06-01
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=DNA fragmentation factor subunit beta; EC=3.-.-.-;AltName: Full=Caspase-activated deoxyribonuclease; Short=CAD; Short=Caspase-activated DNase;AltName: Full=DNA fragmentation factor 40 kDa subunit; Short=DFF-40

Provider

SWISS-PROT

Sequence

Polypeptide 344 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Dffb	DNA fragmentation factor, beta subunit	35	96	3	14

Sequence references in MGI

J:45015 Enari M, et al., A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD [see comments]. Nature. 1998 Jan 1;391(6662):43-50
J:45124 Sakahira H, et al., Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis [see comments]. Nature. 1998 Jan 1;391(6662):96-9
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89