Sequence Detail

ID/Version

O54839 Q8BN22 Q3UPL1 Q52KJ1 Q9JJL1 Q9QYG7 (UniProt | EBI)

Last sequence update: 2010-03-23
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Eomesodermin homolog;AltName: Full=T-box brain protein 2; Short=T-brain-2; Short=TBR-2;

Provider

SWISS-PROT

Sequence

Polypeptide 707 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Eomes	eomesodermin	64	308	4	33

Sequence references in MGI

J:46272 Wattler S, et al., A combined analysis of genomic and primary protein structure defines the phylogenetic relationship of new members if the T-box family. Genomics. 1998 Feb 15;48(1):24-33
J:56361 Kimura N, et al., A novel mammalian T-box-containing gene, Tbr2, expressed in mouse developing brain. Brain Res Dev Brain Res. 1999 Jun 2;115(2):183-93
J:60897 Russ AP, et al., Eomesodermin is required for mouse trophoblast development and mesoderm formation. Nature. 2000 Mar 2;404(6773):95-9
J:64554 Ueno M, et al., Genomic organization, sequence and chromosomal localization of the mouse tbr2 gene and a comparative study with tbr1. Gene. 2000 Aug 22;254(1-2):29-35
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:131055 Arnold SJ, et al., Pivotal roles for eomesodermin during axis formation, epithelium-to-mesenchyme transition and endoderm specification in the mouse. Development. 2008 Feb;135(3):501-11
J:144650 Sessa A, et al., Tbr2 directs conversion of radial glia into basal precursors and guides neuronal amplification by indirect neurogenesis in the developing neocortex. Neuron. 2008 Oct 9;60(1):56-69
J:154842 Pearce EL, et al., Control of effector CD8+ T cell function by the transcription factor Eomesodermin. Science. 2003 Nov 7;302(5647):1041-3
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89