Sequence Detail

ID/Version

O55176 Q99MJ1 Q8CFU2 Q99MJ2 Q99MJ3 Q9DB04 (UniProt | EBI)

Last sequence update: 2006-12-12
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=E3 ubiquitin-protein ligase Praja-1; Short=Praja1; EC=2.3.2.27;AltName: Full=RING-type E3 ubiquitin transferase Praja-1 {ECO:0000305};

Provider

SWISS-PROT

Sequence

Polypeptide 578 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Pja1	praja ring finger ubiquitin ligase 1	9	106	3	6

Sequence references in MGI

J:44194 Mishra L, et al., Praja1, a novel gene encoding a RING-H2 motif in mouse development. Oncogene. 1997 Nov 6;15(19):2361-8
J:64924 Lorick KL, et al., RING fingers mediate ubiquitin-conjugating enzyme (E2)-dependent ubiquitination. Proc Natl Acad Sci U S A. 1999 Sep 28;96(20):11364-9
J:77266 Sasaki A, et al., A RING finger protein Praja1 regulates Dlx5-dependent transcription through its ubiquitin ligase activity for the Dlx/Msx-interacting MAGE/Necdin family protein, Dlxin-1. J Biol Chem. 2002 Jun 21;277(25):22541-6
J:83423 Yu P, et al., PJA1, encoding a RING-H2 finger ubiquitin ligase, is a novel human X chromosome gene abundantly expressed in brain. Genomics. 2002 Jun;79(6):869-74
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89