Sequence Detail

ID/Version

O55240 (UniProt | EBI)

Last sequence update: 1998-06-01
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Retinol dehydrogenase 5; EC=1.1.1.209 {ECO:0000250|UniProtKB:Q92781}; EC=1.1.1.315 {ECO:0000269|PubMed:10588954}; EC=1.1.1.53 {ECO:0000250|UniProtKB:Q92781};AltName: Full=11-cis retinol dehydrogenase {ECO:0000312|EMBL

Provider

SWISS-PROT

Sequence

Polypeptide 318 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Rdh5	retinol dehydrogenase 5	25	109	4	4

Sequence references in MGI

J:46752 Driessen CA, et al., The visual cycle retinol dehydrogenase: possible involvement in the 9-cis retinoic acid biosynthetic pathway. FEBS Lett. 1998 May 29;428(3):135-40
J:47443 Romert A, et al., The identification of a 9-cis retinol dehydrogenase in the mouse embryo reveals a pathway for synthesis of 9-cis retinoic acid. Proc Natl Acad Sci U S A. 1998 Apr 14;95(8):4404-9
J:58911 Gamble MV, et al., Biochemical properties, tissue expression, and gene structure of a short chain dehydrogenase/ reductase able to catalyze cis-retinol oxidation. J Lipid Res. 1999 Dec;40(12):2279-92
J:61553 Romert A, et al., Gene structure, expression analysis, and membrane topology of RDH4. Exp Cell Res. 2000 Apr 10;256(1):338-45
J:77619 Driessen CA, et al., Disruption of the 11-cis-retinol dehydrogenase gene leads to accumulation of cis-retinols and cis-retinyl esters. Mol Cell Biol. 2000 Jun;20(12):4275-87
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:104449 Liden M, et al., The C-terminal region of cis-retinol/androgen dehydrogenase 1 (CRAD1) confers ER localization and in vivo enzymatic function. Exp Cell Res. 2005 Dec 10;311(2):205-17